Red Blood Cell Distribution Width Is Associated with Carotid Atherosclerosis in People with Type 2 Diabetes
Table 1
Clinical characteristics of subjects according to RDW tertiles.
I (10.9–12.1%)
II (12.2–12.6%)
III (12.7–16.0%)
value
N
158
157
154
Male (%)
105 (66.5)
88 (56.1)
100 (64.9)
0.22
Age (years)
54.29 ± 10.57
56.88 ± 11.96
59.92 ± 12.44
<0.01
Diabetes duration (years)
6.78 ± 6.81
7.25 ± 7.57
7.61 ± 7.43
<0.01
BMI (kg/m2)
24.15 ± 2.77
24.58 ± 3.41
25.28 ± 3.57
0.01
SBP (mmHg)
124.18 ± 13.31
127.03 ± 14.19
128.07 ± 14.54
0.04
DBP (mmHg)
77.08 ± 9.06
77.66 ± 8.27
77.48 ± 8.85
0.37
FPG (mmol/L)
9.09 ± 3.94
9.16 ± 3.73
9.57 ± 4.09
0.16
HbA1c (%)
8.62 ± 2.24
8.63 ± 2.43
8.69 ± 2.23
0.39
HbA1c (mmol/mol)
70.7 ± 1.0
70.8 ± 3.1
71.5 ± 0.9
0.41
TC (mmol/L)
4.46 ± 1.06
4.37 ± 1.09
4.55 ± 1.11
0.33
TG (mmol/L)
1.55 (1.15–2.19)
1.36 (1.06–1.99)
1.32 (1.01–1.72)
0.07
LDL-C (mmol/L)
2.55 ± 1.03
2.56 ± 0.93
2.57 ± 0.98
0.76
HDL-C (mmol/L)
1.13 ± 0.33
1.14 ± 0.33
1.15 ± 0.31
0.85
Insulin (mIU/dL)
6.0 (3.0–9.2)
6.75 (2.5–9.8)
7.6 (2.8–11.4)
0.31
HOMA-IR
2.50 (1.07–3.87)
2.31 (1.03-4.25)
2.32 (1.04–4.56)
0.23
Hemoglobin (g/dL)
14.28 ± 1.50
13.78 ± 1.61
13.55 ± 1.63
<0.01
WBC (103/mL)
6.76 ± 1.78
6.84 ± 1.88
6.93 ± 1.63
0.22
Antidiabetic medication (%)
Thiazolidinedione
45 (28.5)
46 (29.3)
41 (26.6)
0.45
Metformin
134 (84.8)
139 (82.5)
128 (83.1)
0.67
Sulfonylurea
80 (50.6)
76 (48.4)
84 (54.5)
0.51
DPP-IV inhibitor
39 (24.7)
37 (23.6)
39 (25.3)
0.20
Insulin
21 (13.3)
25 (15.9)
22(14.3)
0.37
Smoking (%)
50 (31.6)
53 (33.8)
69 (44.8)
0.02
Hypertension (%)
75 (47.4)
83 (52.9)
91 (59.1)
<0.01
Statin use (%)
92 (58.2)
94 (59.9)
99 (64.3)
0.42
Data are represented as the mean ± SD, number (percentage), or median (interquartile range). RDW: red blood cell distribution width; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; HbA1c: hemoglobin A1c; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment of insulin resistance; WBC: white blood cell.
