Review Article

Calcium Signaling in the Ventricular Myocardium of the Goto-Kakizaki Type 2 Diabetic Rat

Table 2

Glucose profile in the GK rat.

ParameterAgeControl versus GKReference

FBG8 w76.2 versus 107.0 (mg/dl)[36]
5, 15, and 22 w6.14 versus 7.49 [5], 7.56 versus 8.71 [15], and 5.26 versus 9.02 [22] (mmol/l)[34]
7, 11, and 15 wIncreased at 7, 11, and 15 (w)[29]
16 w4.8 versus 8.8 (mmol/l)[35]
26 wIncreased[37]
26 w65.8 versus 99.1 (mg/dl)[38]
17 m72.1 versus 151.5 (mg/dl)[39]
18 m95.2 versus 131.4 (mg/dl)[40]
18 m44 versus 51 mg/dl NSD[50]

NFBG8–10 w118.40 versus 166.40 (mg/dl)[41]
11 w7.40 versus 9.18 (mM)[42]
12 w9.02 versus 26.57 (mmol/l)[43]
14–16 w9.4 versus 14.3 (mmol/l)[28]
16 w8.5 versus 12.8 (mmol/l)[30]
18 w6.0 versus 12.7 (mM)[31]
20 w7.5 versus 17.9 (mmol/l)[32]
20 w4.9 versus 8.2 (mmol/l)[33]
5, 15, and 22 w6.14 versus 7.49 [5], 7.56 versus 8.71 [15], and 5.26 versus 9.02 [22] (mmol/l)[34]
26 w204.42 versus 531.71 (mg/dl)[44]
18 and 30 w18.7 versus 24.9 [18] and 19.2 versus 27.6 [30] (μmol/ml)[45]
3, 6, and 15 m49.6 versus 48.4 [3], 48.1 versus 73.3 [6], and 68.6 versus 113.3 [15] (mg/dl)[46]
5–8 m11.3 versus 14.7 (mmol/l)[10]
9–14 m10.3 versus 17.0 (mM)[11]
10 m95.77 versus 143.06 (mg/dl)[47]
10-11 m91.67 versus 161.29 (mg/dl)[48]
17 m101.4 versus 188.8 (mg/dl)[39]

UG16 w0.13 versus 0.73 (g/l)[30]

OGTT8 wElevated at 30, 60, and 120 (min)[36]
15 wElevated at 30, 60, and 120 (min)[29]
16 wElevated at 30 and 60 (min)[37]
26 wElevated at 15 and 60 (min)[44]
26 w83.2 versus 303.4 (mg/dl) at 120 min[38]
10-11 m93.93 versus 236.27 (mg/dl) at 120 min[48]
15 m183.3 versus 276.9 (mg/dl) at 120 min[46]
17 m148.1 versus 570.8 (mg/dl) at 120 min[39]
18 mElevated at 30, 60, 120, and 180 (min)[40]
18 m153.4 versus 436.3 (mg/dl) at 180 min[50]

OGTT15 wIncreased area under curve[29]

HbA1c25 w3.5 versus 5.4 (%)[38]
5–8 m4.0 versus 4.8 (%)[10]

HOMA-IR7, 11, and 15 wIncreased at 7, 11, and NSD 15 (w)[29]

FBG: fasting blood glucose; NFBG: nonfasting blood glucose; UG: urine glucose; OGTT: oral glucose tolerance test; HbA1c: glycated hemoglobin A1c; HOMA-IR: homeostasis model assessment-estimated insulin resistance; NSD: no significant difference. Significant difference.