Review Article
Calcium Signaling in the Ventricular Myocardium of the Goto-Kakizaki Type 2 Diabetic Rat
Table 5
Heart weight and other heart-related measurements in the GK rat.
| Parameter | Age | Control versus GK | Reference |
| HW | 8 w | 0.807 versus 0.927 (g) | [36] | 8–10 w | 0.96 versus 1.05 (g) | [41] | 12 w | 1.14 versus 0.98 (g) | [43] | 15 w | Increased | [29] | 5–8 m | 1700 versus 1460 (mg) | [10] | 9–14 m | 2.0 versus 1.8 g NSD | [11] | 10-11 m | 1.37 versus 1.60 (g) | [48] | 17 m | 1.52 versus 1.50 g NSD | [39] | 18 m | 1.22 versus 1.41 (g) | [40] |
| LVW | 12 w | 0.81 versus 0.68 (g) | [43] | 18 and 30 w | 1.12 versus 0.86 [18] and 1.32 versus 1.03 [30] (g) | [45] | 20 w | Increased | [32] |
| LVT | 8 w | 2.98 versus 3.15 mm NSD | [36] | 18 m | 3.08 versus 3.35 (mm) | [40] |
| RVW | 18 and 30 w | 0.30 versus 0.26 [18] and 0.32 versus 0.28 [30] (g) | [45] |
| HW/BW | 8 weeks | 0.248 versus 0.281 (g/100 g) | [36] | 8–10 w | 4.43 versus 4.33 mg/g NSD | [41] | 15 w | Increased | [29] | 16 w | 2.96 versus 3.73 | [30] | 18 w | 2.2 versus 2.2 NSD | [31] | 20 w | Increased | [32] | 20 w | Increased | [33] | 9–14 m | 3.1 versus 4.5 | [11] | 5–8 m | 3.0 versus 3.8 (mg/g) | [10] | 10-11 m | 3.43 versus 3.61 mg/g NSD | [48] | 18 m | 0.21 versus 0.34 (g/100 g) | [40] | 18 m | 3.36 versus 4.10 (mg/g) | [50] |
| HW/FL | 26 w | 0.44 versus0.49 | [44] |
| LV/BW | 8 w | 1.76 versus 1.98 (mg/g) | [36] | 12 w | 1.85 versus 1.95 (mg/g) | [43] | 18 and 30 w | 2.16 versus 2.24 [18] and 2.06 versus 2.40 [30] (mg/kg) | [45] | 6 m | 0.20 versus 0.24 (%) | [51] |
| RV/BW | 18 and 30 (w) | 0.60 versus 0.71 [18] and 0.50 versus 0.66 [30] (mg/g) | [45] |
| BVW/BW | 14–16 w | Increased | [28] | 18 and 30 w | 2.76 versus 2.94 [18] and 2.56 versus 3.06 [30] (mg/g) | [45] |
| BVW/TL | 14–16 w | Increased | [28] |
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HW: heart weight; LVM: left ventricular weight; LVT: left ventricular thickness; RVW: right ventricular weight; BW: body weight; FL: femur length; BVW: biventricular weight; TL: tibial length; NSD: no significant difference. Significant difference. |