Review Article

Calcium Signaling in the Ventricular Myocardium of the Goto-Kakizaki Type 2 Diabetic Rat

Table 5

Heart weight and other heart-related measurements in the GK rat.

ParameterAgeControl versus GKReference

HW8 w0.807 versus 0.927 (g)[36]
8–10 w0.96 versus 1.05 (g)[41]
12 w1.14 versus 0.98 (g)[43]
15 wIncreased[29]
5–8 m1700 versus 1460 (mg)[10]
9–14 m2.0 versus 1.8 g NSD[11]
10-11 m1.37 versus 1.60 (g)[48]
17 m1.52 versus 1.50 g NSD[39]
18 m1.22 versus 1.41 (g)[40]

LVW12 w0.81 versus 0.68 (g)[43]
18 and 30 w1.12 versus 0.86 [18] and 1.32 versus 1.03 [30] (g)[45]
20 wIncreased[32]

LVT8 w2.98 versus 3.15 mm NSD[36]
18 m3.08 versus 3.35 (mm)[40]

RVW18 and 30 w0.30 versus 0.26 [18] and 0.32 versus 0.28 [30] (g)[45]

HW/BW8 weeks0.248 versus 0.281 (g/100 g)[36]
8–10 w4.43 versus 4.33 mg/g NSD[41]
15 wIncreased[29]
16 w2.96 versus 3.73[30]
18 w2.2 versus 2.2 NSD[31]
20 wIncreased[32]
20 wIncreased[33]
9–14 m3.1 versus 4.5[11]
5–8 m3.0 versus 3.8 (mg/g)[10]
10-11 m3.43 versus 3.61 mg/g NSD[48]
18 m0.21 versus 0.34 (g/100 g)[40]
18 m3.36 versus 4.10 (mg/g)[50]

HW/FL26 w0.44 versus0.49[44]

LV/BW8 w1.76 versus 1.98 (mg/g)[36]
12 w1.85 versus 1.95 (mg/g)[43]
18 and 30 w2.16 versus 2.24 [18] and 2.06 versus 2.40 [30] (mg/kg)[45]
6 m0.20 versus 0.24 (%)[51]

RV/BW18 and 30 (w)0.60 versus 0.71 [18] and 0.50 versus 0.66 [30] (mg/g)[45]

BVW/BW14–16 wIncreased[28]
18 and 30 w2.76 versus 2.94 [18] and 2.56 versus 3.06 [30] (mg/g)[45]

BVW/TL14–16 wIncreased[28]

HW: heart weight; LVM: left ventricular weight; LVT: left ventricular thickness; RVW: right ventricular weight; BW: body weight; FL: femur length; BVW: biventricular weight; TL: tibial length; NSD: no significant difference. Significant difference.