Research Article
Fibrin Clot Strength in Patients with Diabetes Mellitus Measured by Thrombelastography
| | Patient characteristics | Total study population () | No diabetes mellitus () | Diabetes mellitus () | value |
| | Age (years) | 57.1 ± 9.9 | 55.8 ± 9.8 | 58.8 ± 9.7 | 0.005 | | BMI (kg/m2) | 32 ± 7.3 | 31.2 ± 7.6 | 33 ± 6.9 | 0.018 | | Male (%) | 209/354 (59.3%) | 124/202 (61.4%) | 85/152 (55.9%) | 0.3 | | African Americans (%) | 95/354 (26.8%) | 54/202 (26.7%) | 41/109 (27%) | 0.71 | | Hypertension (%) | 320/354 (90.4%) | 172/202 (85.1%) | 148/152 (97.4%) | <0.001 | | Hyperlipidemia (%) | 303/354 (85.6%) | 160/202 (79.2%) | 143/152 (94.1%) | <0.001 | | Coronary artery disease (%) | 310/354 (87.6%) | 171/202 (84.6%) | 139/152 (91.4%) | 0.06 | | History of myocardial infarction (%) | 203/354 (57.3%) | 118/202 (58.4%) | 85/152 (55.9%) | 0.64 | | History of percutaneous coronary intervention (%) | 257/354 (72.6%) | 147/202 (72.7%) | 110/152 (72.4%) | 0.93 | | History of coronary artery bypass grafting (%) | 58/354 (16.4%) | 27/202 (13.4%) | 31/152 (20.4%) | 0.08 | | Congestive heart failure (%) | 63/354 (17.8%) | 32/202 (15.8%) | 31/152 (20.4%) | 0.27 | | Smoking (%) | 162/354 (45.8%) | 106/202 (52.5%) | 56/152 (36.8%) | 0.003 | | Hemoglobin A1c (%) | n/a | 5.82 ± 0.5 | 7.92 ± 1.8 | <0.001 | | Insulin dependent (%) | n/a | n/a | 50/152 (30%) | n/a | | Daily insulin dose (units) | n/a | n/a | 93 ± 74 | n/a | | Fibrinogen (mg/ml) | 3.7 ± 3.1 | 3.2 ± 2 | 4.3 ± 4 | 0.027 | | Plasminogen activator inhibitor-1 (ng/ml) | 120.8 ± 96 | 112 ± 89 | 134.8 ± 106 | 0.34 | | Factor XIIIa (%) | 91.1 ± 30 | 92.1 ± 31 | 89.7 ± 29 | 0.48 |
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