Research Article

Markers of Local Inflammation and Bone Resorption in the Acute Diabetic Charcot Foot

Table 1

Anthropomorphic data for diabetes patients with acute Charcot foot (CF). Test results are from arterial sampling.
(a)

Data listed as mean; range or

Age (years)48.6; 26.0
Sex (m/f)3/2
Affected foot (left/right)1/4
Diabetes type (I/II)2/3
Diabetes duration (years)19.2; 31.0
HbA1c (mmol/mol) (31–44 mmol/mol)73; 53
Ca2+(free, ionized) (mmol/L) (1.18–1.32 mmol/L)1.24; 0.14
PTH (pmol/L) (1.6–6.9 pmol/L)4.5; 4.3
CRP (mg/L) (<10 mg/L)9.8; 15.0
25-OH-vitamin D (nmol/L) (50–160 nmol/L)36.7; 52.6
Alkaline phosphatase (bone specific) (μg/L) (<20 μg/L)$20.3; 7.3
CTX (ng/L) (<630 ng/L)$240; 0.5
P1NP (μg/L) (22–87 μg/L)$48.3; 53.8
Osteocalcin (μg/L) (9–42 μg/L)25.3; 42.1

(b)

Charcot footContralateral footDifference, value

Foot temperature (CF/non-CF) (°C)33.731.1Δ2.6,
Biothesiometry (CF/non-CF) (V)4239Δ3,
Plethysmography (CF/non-CF) (mL/(100 g·min))6.91.8Δ5.1,

Significant at the chosen α-level of 0.05. $Reference range listed for 50 y.o. male where ranges differ with age and/or sex.