Impaired Glucose Metabolisms of Patients with Obstructive Sleep Apnea and Type 2 Diabetes
Table 5
Biochemical parameters of OSA with T2DM patients.
Mild-to-moderate OSA ()
Severe OSA ()
HbA1c (%)
8.71 ± 1.57
8.41 ± 1.38
0.657
Glucose I (mmol/L)a
7.10 (6.86, 8.01)
7.33 (6.47, 7.01)
0.811
Glucose II (mmol/L)
12.00 ± 3.18
11.25 ± 1.82
0.507
Insulin (pmol/L)
61.87 ± 22.36
127.82 ± 57.99
0.010
C-peptide I (nmol/L)
0.73 ± 0.20
1.00 ± 0.58
0.239
C-peptide II (nmol/L)
1.56 (1.28, 3.79)
1.56 (1.23, 3.92)
0.905
HOMA-IR
2.78 (2.20, 2.93)
4.93 (3.73, 8.37)
0.013
Cholesterol (mmol/L)
4.60 ± 0.70
4.36 ± 1.21
0.636
Triglycerides (mmol/L)
2.21 ± 0.95
2.35 ± 0.93
0.760
HDL cholesterol (mmol/L)
1.06 ± 0.23
1.07 ± 0.16
0.882
LDL cholesterol (mmol/L)
3.00 ± 0.63
2.76 ± 0.96
0.575
CRP (mg/L)
3.30 (3.28, 4.16)
3.30 (3.29, 3.90)
0.656
TNF-α (ng/L)
226.50 (203.00, 327.50)
377.00 (195.00, 3099.25)
0.501
IL-6 (ng/L)
9.00 (6.00, 30.00)
18.50 (12.00, 40.50)
0.165
Cortisol (pmol/L)
272.03 ± 52.24
194.46 ± 51.75
0.005
Growth hormone (ng/mL)
0.09 (0.07, 0.13)
0.134 (0.09, 0.28)
0.096
Continuous data with normal distribution are presented as mean ± SD, and continuous data with nonnormal distribution are presented as median (first quartile, third quartile). HOMA-IR: homeostasis model assessment of insulin resistance; HDL: high-density lipoprotein; LDL: low-density lipoprotein; CRP: C-reactive protein; TNF-α: tumor necrosis factor-α; IL-6: interleukin 6 ().aI refers to fasting and II refers to 120 min after 100 g steamed bread meal load.
