Research Article

Genetic Variability of the Glucose-Dependent Insulinotropic Peptide Gene Is Involved in the Premature Coronary Artery Disease in a Chinese Population with Type 2 Diabetes

Table 7

The association of SNPs with CAD risk in overweight/obesity subgroup in dominant inheritance mode.

GeneSNPs genotypeCAD positive n (%)CAD negative n (%)OR (95% CI)OR (95% CI)

GIPrs2291725
C/C142 (47.8)83 (40.5)1.347 (0.939–1.930)0.1051.291 (1.017–1.639)0.036
C/T + T/T155 (52.2)122 (59.5)

OR, 95% CI, and p were calculated by logistic regression analysis after adjustment for other known CAD risk factors (age, BMI, smoking status, dyslipidemia history, hypertension history, and diabetic duration).