AGE/RAGE-Induced EMP Release via the NOX-Derived ROS Pathway
NOX expression in HUVEC suppressed by anti-RAGE antibody and NOX inhibitor. (a) The mRNA expression of NOX-1 and NOX-4 was determined using quantitative real-time PCR. (b) Protein expression of NOX-1 and NOX-4 in each group were analysed by Western blot. Data are expressed as mean ± SD in each group. versus control; versus 400 μg/ml AGEs.