Serum Levels of Interleukin-13 Increase in Subjects with Insulin Resistance but Do Not Correlate with Markers of Low-Grade Systemic Inflammation

Figure 6

Correlation analysis between IL-13 serum levels and parameters of low-grade systemic inflammation in the study population. (a) Correlation analysis between IL-13 serum levels and circulating concentration of TNF-α. (b) Correlation analysis between IL-13 serum levels and the percentage of proinflammatory monocytes Mon-CD11c⁺CD206⁻. (c) Correlation analysis between IL-13 serum levels and circulating concentration of IL-10. (d) Correlation analysis between IL-13 serum levels and the percentage of anti-inflammatory monocytes Mon-CD11c⁻CD206⁺. Serum levels of IL-13 were barely associated with IL-10 but showed no significant correlations with TNF-α, Mon-CD11c⁺CD206⁻, and Mon-CD11c⁻CD206⁺. Mon-CD11c⁺CD206⁻, proinflammatory monocytes that express CD11c but do not express CD206; Mon-CD11c⁻CD206⁺, anti-inflammatory monocytes that express CD206 but do not express CD11c. Coefficients (r) and values were calculated by Pearson’s correlation model. The correlation level was considered significant when .

(a)

(b)

(c)

(d)