Neurophysiological Evidence for a Compensatory Activity during a Simple Oddball Task in Adolescents with Type 1 Diabetes Mellitus

Table 2

Electrophysiological markers: comparisons between the T1D and control groups. The P3b component recorded in response to the visual oddball test was used to assess executive functions. Listed are the values for the target stimulus evaluated from the parietal derivation (P_Z–A₂). The sensory responses from the primary visual cortex were recorded in response to luminance reversal of checkerboard patterns with 40 arcmin and 20 arcmin squares, and peak P100 amplitude and latency were determined in the occipital derivation (O_Z–A₂). Values in the table are expressed as the median and the first and third quartiles.

	T1D patients	Control group
Responses related to executive functions
P3b peak time (ms)	384 (365–396)	368 (348–386)	0.181^b
P3b amplitude (μV)	27.1 (21.2–33.5)	23.6 (19.7–28.8)	0.331^b
P3b area under the curve; Amplitude × time (μV × ms)	2994 (2541–4047)	2446 (1838–2987)	0.035 ^b
Reaction time (ms)	354 (333–384)	348 (332–372)	0.713^b
The sensory responses of the primary visual cortex
R40 peak time (ms)	107 (105–113)	104 (103–106)	0.017 ^b
R40 amplitude (μV)	12.7 (8.6–17.2)	15.7 (12.2–18.9)	0.085^b
R20 peak time (ms)	110 (108–114)	108 (105–107)	0.012 ^a
R20 amplitude (μV)	10.0 (7.84–16.9)	16.0 (13.0–19.2)	0.066^b

^aWilcoxon rank-sum test, ^bStudent’s t-test.