Identification of Potential Therapeutic Targets in the Liver of Pioglitazone-Treated Type 2 Diabetes Sprague-Dawley Rats via Expression Profile Chip and iTRAQ Assay

Table 2

KEGG pathway enrichment via iTRAQ (DM versus Pio).

Number	Pathway ID	Pathway	value
1	ko00830	Retinol metabolism	4.44E − 09
2	ko00140	Steroid hormone biosynthesis	2.49E − 06
3	ko01100	Metabolic pathways	8.68E − 06
4	ko00980	Metabolism of xenobiotics by cytochrome P450	1.54E − 05
5	ko00982	Drug metabolism—cytochrome P450	1.62E − 05
6	ko04976	Bile secretion	7.75E − 05
7	ko03320	PPAR signaling pathway	4.96E − 04
8	ko00590	Arachidonic acid metabolism	6.60E − 04
9	ko00920	Sulfur metabolism	2.41E − 03
10	ko00983	Drug metabolism—other enzymes	4.72E − 03