Intravitreal Bevacizumab Injection Attenuates Diabetic Retinopathy in Adult Rats with Experimentally Induced Diabetes in the Early Stage

Figure 7

Representative photomicrographs of VEGF (red) and NeuN (green) double staining of the retina in the NC11w, DM11w, DM11w + LR, and DM11w + B groups. VEGF immunoreactivity was localized in NeuN-labeled neurons (single arrow) and blood vessels (asterisk). (a, b, c, D-1) The expression of VEGF was notably enhanced in the DM11w and DM11w + LR groups compared with the NC11w and DM11w + B groups. (a, b, c, D-2) Moreover, NeuN-labeled neurons appeared to be condensed and exhibit morphological changes in the DM11w and DM11w + LR groups, in comparison with the NC11w and DM11w + B groups. Bar = 50 μm.

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