Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats

Table 3

Basic characteristics of Sprague-Dawley rats.

	NDC ()	STZ + NS ()	STZ + SPR ()	values
BW (g)	527.10 ± 8.61	218.90 ± 7.65^∗∗∗∗	189.10 ± 10.98^∗∗∗∗	<0.0001
BG (mM)	6.26 ± 0.32	32.69 ± 0.41^∗∗∗∗	30.50 ± 1.14^∗∗∗∗	<0.0001
SBP (mm Hg)	136.10 ± 1.82	147.50 ± 5.38	145.50 ± 6.33	>0.05
DBP (mm Hg)	81.13 ± 5.25	81.43 ± 5.39	77.82 ± 3.70	>0.05
HW (g)	1.94 ± 0.09	1.35 ± 0.12^∗∗∗∗	1.29 ± 0.17^∗∗∗∗	<0.0001
HW/BW (mg/g)	3.94 ± 0.22	6.68 ± 0.70^∗∗∗∗	7.22 ± 1.12^∗∗∗∗	<0.0001

NDC: nondiabetic controls; STZ: streptozotocin; NS: saline; SPR: spironolactone; BW: body weight; BG: blood glucose; SBP: systolic blood pressure; DBP: diastolic blood pressure; HW: heart weight; HW/BW: heart weight/body weight. , data are . and vs. NDC group.