Research Article
Predictors of Effectiveness of Glucagon-Like Peptide-1 Receptor Agonist Therapy in Patients with Type 2 Diabetes and Obesity
(a) Hormone levels in the study group at baseline: comparison with reference range |
| | Hormones | Patients on the aGLP-1, | Reference range |
| | Adiponectin (mcg/ml) | | | | Men | 8.9 (6.8; 17.1) | >6 | | Women | 10.1 (8.2; 13.8) | 9-12 | | Leptin (ng/ml) | | | | Men | 45.0 (8.0; 79.0) | 0.5-13.8 | | Women | 32.5 (13.5; 52.5) | 1.1-27.6 | | Ghrelin fasting (pg/ml) | 1.6 (0.8; 2.7) | 8.502-16.6 | | Ghrelin after test (pg/ml) | 2.7 (1.4; 3.5) | ↓ 25-55% from baseline |
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2 hours after breakfast in the meal tolerance test. See reference [ 34]. |
(b) Hormone levels in the study group at baseline: comparison with control group |
| | Hormones | Patients on aGLP-1, | Control group, |
| | GLP-1 fasting (mmol/l) | 0.07 (0.01; 0.14) | 0.17 (0.12; 0.27) | | GIP (pg/ml) | 391.6 (326.6; 461.4) | 574 (520.4; 744.5) |
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