Effects of Negative Pressure Wound Therapy on Levels of Angiopoetin-2 and Other Selected Circulating Signaling Molecules in Patients with Diabetic Foot Ulcer
Table 1
Clinical characteristics of the study groups.
Entire group ()
MV subgroup ()
NPWT
ST
value
NPWT
ST
value
Sex M/F ()
42/7
15/5
0.31
17/2
8/2
0.59
Age (year)
0.93
0.06
BMI (kg/m2)
0.38
27.7 (25.7-30.9)
27.3 (25.6-29.1)
0.91
Duration of diabetes (year)
0.25
0.23
Insulin treatment Y/N ()
48/1
18/2
0.20
18/1
9/1
1.00
Duration of insulin therapy (year)
5.0 (1.0-10.0)
6.0 (3.0-15.0)
0.38
4.0 (1.0-8.0)
10.0 (3.0-13.5)
0.10
Daily dose of insulin (unit)
50.0 (40.0-70.0)
50.0 (30.0-60.0)
0.70
0.96
HbA1c (mmol/mol)
51.9 (43.2-58.5)
56.3 (43.7-66.7)
0.25
47.5 (41.0-56.3)
48.1 (39.9-60.7)
0.96
HbA1c (%)
6.9 (6.1-7.5)
7.3 (6.2-8.3)
0.25
6.5 (5.9-7.3)
6.6 (5.8-7.7)
0.96
eGFR (mL/min/1.73 m2)
88.0 (63.0-93.0)
80.5 (58.0-95.5)
0.74
87.0 (55.0-92.0)
76.0 (53.0-98.0)
0.80
Wound area (cm2)
10.3 (4.2-18.9)
1.3 (0.9-3.4)
0.0001
12.6 (3.8-19.2)
1.0 (0.8-1.4)
0.001
Duration of the wound (week)
12.2 (10.1-23.7)
10.3 (4.1-18.0)
0.16
12.0 (10.1-22.9)
10.0 (5.1-24.9)
0.30
Data shown as number of cases, (for normally distributed variables) or median and IQR (for nonnormally distributed variables).