Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study

Table 2

Relations of DM status to circulating BDNF, IGF-1, and VEGF levels adjusted for age.

	Participants without DM	Participants with DM	Age-adjusted
IGF-1, ng/ml			0.014
VEGF, pg/ml median (Q1, Q3)	267 (159, 452)	276 (152, 428)	0.58
BDNF, pg/ml			0.48

Abbreviations: IGF-1: insulin-like growth factor-1; VEGF: vascular endothelial growth factor; BDNF: brain-derived neurotrophic factor; DM: diabetes mellitus. values were calculated using analysis of covariance (ANCOVA). For variables not normally distributed, a transformation was applied to make the distribution more normal. Significant values () were set in bold for emphasis.