Journal of Diabetes Research / 2019 / Article / Fig 7

Research Article

Effect of Baoshenfang Formula on Podocyte Injury via Inhibiting the NOX-4/ROS/p38 Pathway in Diabetic Nephropathy

Figure 7

Effect of NOX-4 siRNA on p38 pathway-induced apoptosis in HG cultured podocytes. (a) Representative band of p38 and P-p38 protein in cultured podocyte. (b, c) Comparison of the grey values of P-p38 and p38 protein in cultured podocyte. NOX-4 siRNA significantly decreased the expression P-p38 protein compared with the HG group. (d) Comparison of caspase-3 activity in cultured podocyte. NOX-4 siRNA significantly decreased the caspase-3 activity in HG cultured podocytes. and versus NG. and versus HG.

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