Lack of Associations between Elevated Serum Uric Acid and Components of Metabolic Syndrome Such as Hypertension, Dyslipidemia, and T2DM in Overweight and Obese Chinese Adults
Table 1
Correlations between serum uric acid and attributes among 409 participants.
Attribute
Uric acid,
Interpretation of correlation
Mean
SD
Min
Max
95% CI
Uric acid (μmol/L)
407
100
205
758
—
—
—
—
Age (y)
31.0
9.2
18
71
-0.33
-0.41–0.24
<0.01
Negative
BMI (kg/m2)
33.4
5.1
24.6
55.1
0.30
0.21–0.39
<0.01
Positive
Muscle mass (kg)
53.6
9.8
30.2
90.0
0.45
0.37–0.52
<0.01
Positive
SBP (mmHg)
132
14.4
100
188
0.14
0.05–0.24
<0.01
Positive
ALT (IU/L)
58.1
48.7
5
258
0.40
0.31–0.48
<0.01
Positive
Creatinine (μmol/L)
62.0
14.0
33
114
0.47
0.39–0.55
<0.01
Positive
Cholesterol (mmol/L)
5.2
1.0
2.39
12.1
0.10
0.01–0.20
0.04
Weakly positive
HDL-C (mmol/L)
1.6
1.0
0.61
7.20
0.11
0.01–0.20
0.03
Weakly positive
LDL-C (mmol/L)
2.8
1.0
0.53
5.49
-0.04
—
0.38
—
Triglyceride (mmol/L)
1.90
1.5
0.42
23.5
0.04
—
0.44
—
FBG (mmol/L)
5.8
1.5
3.72
17.7
0.04
—
0.38
—
HbA1c (%)
5.7
1.0
4.4
12.6
0.05
—
0.45
—
HOMA-IR
7.2
5.3
0.71
43.50
0.19
0.09–0.28
<0.01
Positive
UMA (mg/g creatinine)
6.7
15.8
0.21
205.0
0.09
—
0.06
—
Abbreviations: CI: confidence interval; SD: standard deviation; SBP: systolic blood pressure; ALT: alanine aminotransferase; HDL-C: HDL cholesterol; LDL-C: LDL cholesterol; FBG: fasting blood glucose; HOMA-IR: homeostatic model assessment index of insulin resistance; UMA: urine microalbumin.