Research Article
Single Nucleotide Polymorphisms in CDKAL1 Gene Are Associated with Risk of Gestational Diabetes Mellitus in Chinese Population
Table 3
Association of haplotypes in the CDKAL1 gene with gestational diabetes mellitus.
| SNP combinations | Frequency (%) | ORa | 95% CI | b |
| Block 4 | rs4712527 rs9356744 rs9368222 rs7748720 rs9295478 rs6935599 rs7747752 rs6928012 | AGAAAGGG | 39.88 | 1 | | | AACAGACA | 31.24 | 0.82 | 0.62-1.07 | 0.145 | GACGGACG | 14.08 | 0.52 | 0.37-0.74 | 0.0003 | AACAAGGG | 6.72 | 0.98 | 0.62-1.55 | 0.931 | Rare (<0.05) | 8.08 | 0.86 | 0.56-1.33 | 0.505 |
| Block 5 | | | | | rs13217519 rs9350276 | | | | | GA | 36.73 | 1 | | | AA | 35.32 | 1.03 | 0.79-1.33 | 0.845 | AG | 27.94 | 0.71 | 0.54-0.93 | 0.015 |
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