Combined Administration of Streptozotocin and Sucrose Accelerates the Appearance of Type 2 Diabetes Symptoms in Rats

Table 5

Body weight gain (g in body weight) and food intake daily (g of food/100 g of body weight). The data shown are of the rats of experimental protocols A and B. Body weight and food intake were monitored daily for 6 weeks (8-4 weeks of age). Values are expressed as the median and interquartile range (IQR) (p25-p75). Variation between more than two groups was measured by the Kruskal-Wallis test followed by the Dunn Multiple Comparison Test. The asterisk denotes that the data are significantly different from the Control group (, , and ), and the plus sign denotes that the data are significantly different from the Stz70 group (⁺, ⁺⁺, and ⁺⁺⁺).

	Body weight gain		Food intake daily
	Male	Female	Male	Female
Control	152.6 (138.7-170)	78.2 (66.1-85)	6.9 (6.5-7.4)	7.7 (7.1-8.4)
Stz70	150.5 (122.2-166.4)	68.1 (56.3-77.7)	7.6 (6.8-8.9)	8 (7.3-10.3)
Stz90	99.9^+ (74.3-121.5)	51 (36.1-65.9)	12.2^+++ (11.3-12.9)	13.2^++ (11.8-14.1)
C+10% 7w	178.6 (137.8-190)	62.6 (62-77.8)	6.9 (6.5-7.1)	7.2 (6.4-7.6)
C+10% 11w	182.6 (179-201.8)	93.3 (79.5-95.1)	4.6 (4.1-4.9)	4.5 (3.8-5)
C+30% 7w	177 (160.5-202.8)	66.6 (50.5-74.1)	6.9 (6.1-7.6)	7.7 (5.9-8.8)
C+30% 11w	165.7 (128.9-185.3)	83.1 (70.8-113.6)	4.5 (4-4.7)	3.8 (3.3-5.7)
Stz70+10% 7w	106.8 (90.6-131.7)	72.3 (62.6-108.7)	12.3^+++ (11.3-13.5)	7.8 (6.5-9.3)
Stz70+10% 11w	89.9^++ (56.6-97.9)	88.8 (78.2-105.3)	4.6^++ (4.1-5.4)	5.5^+++ (4.4-5.6)
Stz70+30% 7w	145.4 (141.8-150)	67.4 (66.9-87.3)	9.5 (6.6-10.7)	7.3+ (6.7-8)
Stz70+30% 11w	130.9 (102-170)	83.6+ (74.4-92.9)	4.3^+++ (3.8-4.4)	4.2^+++ (3.8-4.9)