Type 2 Diabetes Mellitus Increases the Risk to Hip Fracture in Postmenopausal Osteoporosis by Deteriorating the Trabecular Bone Microarchitecture and Bone Mass

Table 1

Structural parameters of trabecular bone within the femoral head for four groups at different time points. Data presented as the .

(a)

VOX BV/TV (%)
	8 weeks	10 weeks	14 weeks
Gp. I
Gp. II		^a	^b
Gp. III
Gp. IV			^c,d

^a% difference to Gp. I (-23.80) (). ^b% difference to Gp. I (-24.1) (). ^c% difference to Gp. III (-25.3) (). ^d% difference to Gp. III (-30.15) ().

(b)

TRI-BS/TV (mm^-1)
	8 weeks	10 weeks	14 weeks
Gp. I	14.69 ± 1.02	14.21 ± 1.14	12.88 ± 0.86
Gp. II	14.77 ± 0.74	13.93 ± 0.47	14.07 ± 0.35
Gp. III	14.02 ± 1.30	13.33 ± 0.62	15.00 ± 1.22^a
Gp. IV	15.14 ± 1.11	14.90 ± 1.91	13.67 ± 0.32

^a% difference to Gp. I (16.52) ().

(c)

DT-TB.N (1/mm)
	8 weeks	10 weeks	14 weeks
Gp. I
Gp. II		^a	^b
Gp. III			^c,d,e
Gp. IV

^a% difference to Gp. I (21.02) (). ^b% difference to 8 weeks in Gp. II (-19.10) (). ^c% difference to 8 weeks in Gp. II (-20.47) (). ^d% difference to Gp. II (22.91) (). ^e% difference to Gp. IV (28.78) ().

(d)

DT-Tb.Th (μm)
	8 weeks	10 weeks	14 weeks
Gp. I
Gp. II			^a
Gp. III
Gp. IV			^b

^a% difference to Gp. I (-20) (). ^b% difference to Gp. I (-20) ().

(e)

DT-Tb.Sp (μm)
	8 weeks	10 weeks	14 weeks
Gp. I
Gp. II		^a,b
Gp. III			^c,d,e
Gp. IV

^a% difference to Gp. I (20) (). ^b% difference to Gp. I (-25) (). ^c% difference to 8 weeks in Gp. II (20) (). ^d% difference to Gp. II (33) (). ^e% difference to Gp. IV (44) ().

(f)

Mean 1/v BMD
	8 weeks	10 weeks	14 weeks
Gp. I
Gp. II		^a
Gp. III
Gp. IV			^b,c

^a% difference to Gp. I (-17.97) (). ^b% difference to Gp. I (-20.5) (). ^c% difference to Gp. III (-24.5) ().

(g)

TRI-SMI
	8 weeks	10 weeks	14 weeks
Gp. I
Gp. II	a
Gp. III			^b
Gp. IV

^a% difference to Gp. IV (-69) (). ^b% difference to Gp. IV (-86) ().

(h)

Conn-Dens
	8 weeks	10 weeks	14 weeks
Gp. I
Gp. II
Gp. III
Gp. IV