Ethyl Pyruvate Prevents Renal Damage Induced by Methylglyoxal-Derived Advanced Glycation End Products

<div>Renal histopathology. (a) Periodic acid-Schiff (PAS) staining of renal cortex. ×200 magnification. (b) Immunohistochemistry of <i>α</i>-SMA. ×200 magnification. NOR: normal control rats; MGO: exogenous MGO-injected rats; AG: MGO treated with aminoguanidine (50 mg/kg); EP10: MGO treated with EP (10 mg/kg); EP25: MGO treated with EP (25 mg/kg); EP50: MGO treated with EP (50 mg/kg).</div>

Journal of Diabetes Research

fig3

Figure 3

Figure 3: Ethyl Pyruvate Prevents Renal Damage Induced by Methylglyoxal-Derived Advanced Glycation End Products 