Gender-Specific Independent and Combined Effects of the Cortisol-to-Cortisone Ratio and 11-Deoxycortisol on Prediabetes and Type 2 Diabetes Mellitus: From the Henan Rural Cohort Study
Table 1
Basic characteristics of the NGT and prediabetes participants.
Male
Female
Prediabetes
NGT
value
Prediabetes
NGT
value
Subjects,
342
342
536
536
Age (years)
Matched
Matched
BMI (kg/m2)
<0.001
0.002
Current smoker, (%)
158 (46.2)
174 (50.9)
0.221
0
2 (0.4)
0.25
Alcohol drinker, (%)
84 (24.6)
102 (29.8)
0.122
10 (1.9)
12 (2.2)
0.667
Physical activity, (%)
0.465
0.866
Low
119 (34.8)
104 (30.4)
110 (20.5)
103 (19.2)
Mediate
119 (34.8)
129 (37.7)
308 (57.5)
313 (58.4)
High
104 (30.4)
109 (31.9)
118 (22.0)
120 (22.4)
Middle school or below, (%)
45 (13.2)
43 (12.6)
0.819
33 (6.2)
26 (4.9)
0.349
Per capita monthly income, (%)
0.076
0.563
<500 (RMB)
151 (44.2)
128 (37.4)
211 (39.4)
214 (39.9)
~500 (RMB)
107 (31.3)
105 (30.7)
182 (34.0)
167 (31.2)
≥1000 (RMB)
84 (24.6)
109 (31.9)
143 (26.7)
155 (28.9)
Marital status, (%)
0.605
0.219
Married/cohabiting
303 (88.6)
305 (89.2)
472 (88.1)
473 (88.2)
Widowed
23 (6.7)
23 (6.7)
61 (11.4)
63 (11.8)
Divorced/separated
4 (1.2)
1 (0.3)
3 (0.6)
0
Unmarried
12 (3.5)
13 (3.8)
0
0
Family history of T2DM, (%)
5 (1.5)
5 (1.5)
0.624
8 (1.5)
9 (1.7)
0.500
SBP (mmHg)
0.001
0.072
TC (mmol/L)
<0.001
<0.001
TG (mmol/L)
0.001
0.048
HDL-C (mmol/L)
0.035
0.151
LDL-C (mmol/L)
<0.001
<0.001
F/E
11.62 (8.10-16.62)
11.25 (8.44-15.54)
0.345
11.33 (8.15-16.29)
11.41 (8.50-15.86)
0.561
11-Deoxycortisol (ng/mL)
0.30 (0.20-0.50)
0.40 (0.20-0.60)
0.001
0.30 (0.20-0.50)
0.30 (0.20-0.50)
0.028
Abbreviation: NGT: normal glucose tolerance; T2DM: type 2 diabetes mellitus; BMI: body mass index; RMB: renminbi; SBP: systolic blood pressure; TC: total cholesterol; TG: triacylglycerol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; F/E: cortisol-to-cortisone ratio; SD: standard deviation. Data are presented as (%) for categorical data and or median (interquartile range) for continuous data.
