Gender-Specific Independent and Combined Effects of the Cortisol-to-Cortisone Ratio and 11-Deoxycortisol on Prediabetes and Type 2 Diabetes Mellitus: From the Henan Rural Cohort Study
Table 2
Basic characteristics of the NGT and T2DM participants.
Male
Female
T2DM
NGT
value
T2DM
NGT
value
Subjects,
339
339
553
553
Age (years)
Matched
Matched
BMI (kg/m2)
<0.001
<0.001
Current smoker, (%)
144 (42.5)
173 (51.0)
0.026
2 (0.4)
3 (0.5)
0.687
Alcohol drinker, (%)
113 (33.3)
102 (30.1)
0.364
7 (1.3)
12 (2.2)
0.247
Physical activity, (%)
0.197
0.048
Low
114 (33.6)
100 (29.5)
139 (25.1)
105 (19.0)
Mediate
107 (31.6)
129 (38.1)
300 (54.2)
325 (58.8)
High
118 (34.8)
110 (32.4)
114 (20.6)
123 (22.2)
Middle school or below, (%)
271 (79.9)
298 (87.9)
0.003
526 (95.1)
526 (95.1)
0.555
Per capita monthly income, (%)
0.439
0.748
<500 (RMB)
137 (40.4)
128 (37.8)
226 (40.9)
223 (40.3)
~500 (RMB)
88 (26.0)
103 (30.4)
162 (29.3)
173 (31.3)
≥1000 (RMB)
114 (33.6)
108 (31.9)
165 (29.8)
157 (28.4)
Marital status, (%)
0.760
0.730
Married/cohabiting
298 (87.9)
302 (89.1)
495 (89.5)
489 (88.5)
Widowed
23 (6.8)
23 (6.8)
54 (9.8)
61 (11.0)
Divorced/separated
3 (0.9)
1 (0.3)
4 (0.7)
3 (0.5)
Unmarried
15 (4.4)
13 (93.8)
0
0
Family history of T2DM, (%)
17 (5.0)
5 (1.5)
0.009
32 (5.8)
10 (1.8)
0.001
SBP (mmHg)
0.001
<0.001
TC (mmol/L)
<0.001
<0.001
TG (mmol/L)
0.001
<0.001
HDL-C (mmol/L)
0.001
<0.001
LDL-C (mmol/L)
0.576
0.047
F/E
11.17 (8.13-15.58)
11.33 (8.46-15.78)
0.296
10.28 (7.30-15.48)
11.45 (8.51-15.76)
0.967
11-Deoxycortisol (ng/mL)
0.30 (0.20-0.50)
0.20 (0.30-0.60)
0.572
0.30 (0.20-0.50)
0.30 (0.20-0.50)
0.649
Abbreviation: NGT: normal glucose tolerance; T2DM: type 2 diabetes mellitus; BMI: body mass index; RMB: renminbi; SBP: systolic blood pressure; TC: total cholesterol; TG: triacylglycerol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; F/E: cortisol-to-cortisone ratio; SD: standard deviation. Data are presented as (%) for categorical data and or median (interquartile range) for continuous data.
