Journal of Diabetes Research / 2019 / Article / Tab 2

Research Article

Gender-Specific Independent and Combined Effects of the Cortisol-to-Cortisone Ratio and 11-Deoxycortisol on Prediabetes and Type 2 Diabetes Mellitus: From the Henan Rural Cohort Study

Table 2

Basic characteristics of the NGT and T2DM participants.

MaleFemale
T2DMNGT valueT2DMNGT value

Subjects, 339339553553
Age (years)MatchedMatched
BMI (kg/m2)<0.001<0.001
Current smoker, (%)144 (42.5)173 (51.0)0.0262 (0.4)3 (0.5)0.687
Alcohol drinker, (%)113 (33.3)102 (30.1)0.3647 (1.3)12 (2.2)0.247
Physical activity, (%)0.1970.048
 Low114 (33.6)100 (29.5)139 (25.1)105 (19.0)
 Mediate107 (31.6)129 (38.1)300 (54.2)325 (58.8)
 High118 (34.8)110 (32.4)114 (20.6)123 (22.2)
Middle school or below, (%)271 (79.9)298 (87.9)0.003526 (95.1)526 (95.1)0.555
Per capita monthly income, (%)0.4390.748
 <500 (RMB)137 (40.4)128 (37.8)226 (40.9)223 (40.3)
 ~500 (RMB)88 (26.0)103 (30.4)162 (29.3)173 (31.3)
 ≥1000 (RMB)114 (33.6)108 (31.9)165 (29.8)157 (28.4)
Marital status, (%)0.7600.730
 Married/cohabiting298 (87.9)302 (89.1)495 (89.5)489 (88.5)
 Widowed23 (6.8)23 (6.8)54 (9.8)61 (11.0)
 Divorced/separated3 (0.9)1 (0.3)4 (0.7)3 (0.5)
 Unmarried15 (4.4)13 (93.8)00
Family history of T2DM, (%)17 (5.0)5 (1.5)0.00932 (5.8)10 (1.8)0.001
SBP (mmHg)0.001<0.001
TC (mmol/L)<0.001<0.001
TG (mmol/L)0.001<0.001
HDL-C (mmol/L)0.001<0.001
LDL-C (mmol/L)0.5760.047
F/E11.17 (8.13-15.58)11.33 (8.46-15.78)0.29610.28 (7.30-15.48)11.45 (8.51-15.76)0.967
11-Deoxycortisol (ng/mL)0.30 (0.20-0.50)0.20 (0.30-0.60)0.5720.30 (0.20-0.50)0.30 (0.20-0.50)0.649

Abbreviation: NGT: normal glucose tolerance; T2DM: type 2 diabetes mellitus; BMI: body mass index; RMB: renminbi; SBP: systolic blood pressure; TC: total cholesterol; TG: triacylglycerol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; F/E: cortisol-to-cortisone ratio; SD: standard deviation. Data are presented as (%) for categorical data and or median (interquartile range) for continuous data.

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