Hyperinsulinemia Can Cause Kidney Disease in the IGT Stage of OLETF Rats via the INS/IRS-1/PI3-K/Akt Signaling Pathway

Figure 5

Expression of megalin and cubilin by immunohistochemistry in a light microscope: (a) megalin in the control group (×400), (b) megalin in the NGT group (×400), (c) megalin in the IGT group (×400), (d) megalin in the DM group (×400), (e) megalin in the DKD group (×400), (f) cubilin in the control group (×400), (g) cubilin in the NGT group (×400), (h) cubilin in the IGT group (×400), (i) cubilin in the DM group (×400), and (j) cubilin in the DKD group (×400).

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