Hyperinsulinemia Can Cause Kidney Disease in the IGT Stage of OLETF Rats via the INS/IRS-1/PI3-K/Akt Signaling Pathway

Table 3

Alteration of glomerular function marker in different stages of type 2 DM.

Group	24 h UMA (μg/24 h)	Scr (μmol/L)	BUN (mmol/L)
Control
NGT
IGT
DM		^ab
DKD	^abcd	^abc	^abc
	0.001	0.001	0.008

^a vs. the control group. ^b vs. NGT. ^c vs. IGT. ^d vs. DM.