Research Article

Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter

Figure 1

Experimental design. Thirty-day-old male mice were randomly housed in two groups: mice receiving standard chow (CTRL, ) or high-fat diet (HFD, ) for 16 weeks. After 16 weeks, CTRL and HFD mice were randomly subdivided and exposed to a nasotropic instillation of PM2.5 or saline solution, then rested, or subjected to moderate- or high-intensity physical exercise. The mice were euthanized by decapitation, and blood and lungs were collected for biochemical analyses.