Research Article

Effects of Genetic Variants of Nuclear Receptor Y on the Risk of Type 2 Diabetes Mellitus

Table 2

Association between NF-YA SNPs and the risk of T2DM under different genetic models.

SNPGenetic model valueOR [95% CI]

rs2268188Dominant(TG+GG) vs. TT0.0261.36 [1.04–1.79]
rs6918969Dominant(TC+CC) vs. TT0.0031.54 [1.16–2.03]
rs28869187Dominant(AC+CC) vs. AA0.0161.40 [1.07–1.84]
rs35105472RecessiveGG vs. (CG+CC)0.0741.62 [0.95–2.77
rs76109475Dominant(AG+AA) vs. GG0.5861.08 [0.82–1.42]

For each SNP, only the best genetic model determined by Akaike’s information criterion (AIC) is provided. The ORs and CIs that are statistically significant are bolded, along with the rs number of the corresponding SNP.