The Role of the Autonomic Nervous System on Cardiac Rhythm during the Evolution of Diabetes Mellitus Using Heart Rate Variability as a Biomarker

Age and development of diabetes mellitus alter the heart rate variability in the cDM model. (a, d) In adulthood, the morphology of the Poincaré plot is an ellipse with axe major SD2 and axe minor SD1, and the SD1/SD2 index was 0.5 for the PP interval and for RR interval . (b, e) At 30 years of age with 8 years’ development of DM, the data showed the function of the parasympathetic system. (c, f) At 40 years of age with 15 years’ development of DM, the data showed that the nervous system ceased to function, and there were no changes in SD1 and SD2. Index with respect to control.