Research Article

Polymorphisms in NLRP1 Gene Are Associated with Type 1 Diabetes

Table 2

Clinical and biochemical characteristics of cases and controls.

CharacteristicCasesControls value

Sample size510531
Sex (men/women)275/235273/2580.418
Age (year)22 (13-34)42 (32-51)<0.001
BMI (kg/m2)18.70 (16.49-20.70)22.60 (20.40-24.70)<0.001
T1D duration (month)5.00 (0.50-21.50)
FPG (mmol/L)8.91 (6.11-14.40)4.87 (4.45-5.30)<0.001
PPG (mmol/L)14.90 (9.90-20.70)5.60 (4.70-6.40)<0.001
FCP (pmol/L)77.50 (17.79-164.10)
PCP (pmol/L)142.21 (39.60-279.20)
HbA1c (%)10.00 (7.80-12.80)

BMI: body mass index; FPG: fasting plasma glucose; PPG: 2 h postprandial plasma glucose; FCP: fasting C-peptide; PCP: 2 h postprandial C-peptide; HbA1c: glycated hemoglobin.