Effect of the Interaction between Obstructive Sleep Apnea and Lipoprotein(a) on Insulin Resistance: A Large-Scale Cross-Sectional Study

Figure 2

Multiplicative interaction between AHI quartiles and Lp(a) quartiles on the association with the presence of insulin resistance. More significant trends in the relationship between AHI quartiles and insulin resistance were found in the lower Lp(a) quartiles, indicating significant positive interaction. Odds ratios and P values were calculated with logistic regression analyses after adjusting for age, gender, BMI, waist-to-hip circumference ratio, MAP, current smoking status, current drinking status, TC, TG, HDL-C, LDL-C, ApoA-I, and ApoB. AHI quartiles 1-4 correspond to the AHI range of ≤7, 7.1-28, 28.1-57, and >57 events/h, respectively. Lp(a) quartiles 1-4 correspond to the serum Lp(a) concentration range of ≤3.90, 3.91-7.40, 7.41-15.10, and >15.10 mg/dL, respectively.