Journal of Diabetes Research / 2019 / Article / Tab 3

Research Article

Effect of the Interaction between Obstructive Sleep Apnea and Lipoprotein(a) on Insulin Resistance: A Large-Scale Cross-Sectional Study

Table 3

The odds ratios for the presence of insulin resistance across AHI or Lp(a) quartiles.

Quartile 1Quartile 2Quartile 3Quartile 4P for linear trend

AHI quartiles
n (cases/participants)169/1,053334/1,031424/1,017668/1,051
Unadjusted12.51 (2.03, 3.10)3.74 (3.05, 4.61)9.12 (7.43, 11.25)<0.001
Adjusted11.61 (1.27, 2.05)1.92 (1.50, 2.46)2.87 (2.23, 3.70)<0.001
Lp(a) quartiles
n (cases/participants)456/1,026427/1,062371/1,032341/1,032
Unadjusted1.62 (1.36, 1.94)1.35 (1.14, 1.63)1.14 (0.95, 1.36)1<0.001
Adjusted1.40 (1.12, 1.74)1.21 (0.98, 1.50)1.16 (0.93, 1.43)10.029

Odds ratios, 95% confidence intervals, and P values were calculated using logistic regression analyses. Insulin resistance was defined as the HOMA-IR index > 3. AHI quartiles 1-4 correspond to the AHI range of ≤7, 7.1-28, 28.1-57, and >57 events/h, respectively. Lp(a) quartiles 1-4 correspond to the serum Lp(a) concentration range of ≤3.90, 3.91-7.40, 7.41-15.10, and >15.10 mg/dL, respectively. Adjusted variables include Lp(a) or AHI quartiles, age, gender, BMI, waist-to-hip circumference ratio, MAP, current smoking status, current drinking status, TC, TG, HDL-C, LDL-C, ApoA-I, and ApoB.

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