Research Article
Renal Effects of Sulodexide in Type 2 Diabetic Patients without Nephrotic Range Proteinuria
Table 2
Changes of renal outcomes and metabolic parameters after 12 months.
| Parameters | Sulodexide group () | Control group () | Baseline | 12 months | value | Baseline | 12 months | value |
| BUN (mg/dL) | | | 0.481 | | | 0.001 | Creatinine (mg/dL) | | | 0.001 | | | 0.001 | GFR (mL/min/1.73 m2) | | | 0.001 | | | 0.001 | Urine protein creatinine ratio (g/gCr) | 0.66 (0.23, 0.67) | 0.67 (0.17, 1.51) | 0.108 | 0.9 (0.3, 1.78) | 1.16 (0.44, 2.23) | 0.001 | Systolic blood pressure (mmHg) | | | 0.078 | | | 0.006 | Diastolic blood pressure (mmHg) | | | 0.679 | | | 0.132 | Fasting plasma glucose (mg/dL) | | | 0.452 | | | 0.829 | Hemoglobin A1C (%) | | | 0.131 | | | 0.283 |
|
|
Data presents as mean with SD and median with interquartile range (IQR). BUN: blood urea nitrogen; GFR: glomerular filtration rate.
|