Research Article

Renal Effects of Sulodexide in Type 2 Diabetic Patients without Nephrotic Range Proteinuria

Table 3

Percentage of changes during 12 months in renal and metabolic outcomes between groups.

Percentage of changes with interquartile rangeSulodexide group
()
Control group
()
value between groups

BUN (mg/dL)6.0 (-11.6 to 26.6)12.7 (-4.0 to 33.9)0.316
Creatinine (mg/dL)15.8 (5.3 to 27.3)12.3 (4.2 to 18.8)0.198
GFR (mL/min/1.73 m2)-15.5 (-25.8 to -4.9)-12.4 (-17.5 to -6.1)0.201
Urine protein creatinine ratio (g/gCr)-17.7 (-53.1 to 3.2)19.4 (10.3 to 37.6)0.001
Systolic blood pressure (mmHg)-1.5 (-8.3 to 5.4)4.5 (-1.8 to 10.5)0.004
Diastolic blood pressure (mmHg)0 (-8.2 to 6.8)4.9 (-3.8 to 11.9)0.077
Fasting plasma glucose (mg/dL)0.8 (-13.9 to 10.9)5.5 (-6.3 to 16.9)0.241
Hemoglobin A1C (%)-1.6 (-10.9 to 7.7)1.5 (-2.6 to 6.8)0.254

Data presents as percentage with interquartile range. BUN: blood urea nitrogen; GFR: glomerular filtration rate.