Poor Control of Plasma Triglycerides Is Associated with Early Decline of Estimated Glomerular Filtration Rates in New-Onset Type 2 Diabetes in China: Results from a 3-Year Follow-Up Study
Table 2
Characteristics of study participants by △eGFR.
Characteristics
Group 1 ()
Group 2 ()
Group 3 ()
Female (, %)
Baseline
57 (60.6%)
69 (72.6%)
69 (73.4%)
Age (years)
Baseline
Baseline
BMI (kg/m2)
Follow-up
△
-1.35 (-2.40 to -0.46)
-1.06 (-1.82 to 0.02)a
-0.57 (-1.74 to 0.31)a
Baseline
SBP (mmHg)
Follow-up
△
-8.50 (-16.00 to 2.00)
-12.00 (-23.00 to -1.00)
-11.00 (-22.00 to 2.00)
Baseline
DBP (mmHg)
Follow-up
△
-2.00 (-8.00 to 4.00)
-5.00 (-12.00 to 1.00)
-3.00 (-10.00 to 5.00)
Baseline
FBG (mmol/L)
Follow-up
△
-0.23 (-0.93 to 0.51)
0.25 (-0.88 to 0.71)
0.21 (-0.48 to 1.08)a
Baseline
PBG (mmol/L)
Follow-up
△
1.01 (-1.11 to 3.05)
1.68 (-1.37 to 3.17)
1.77 (-0.22 to 4.35)
Baseline
HbA1C (%)
Follow-up
△
-0.30 (-0.80 to -0.18)
-0.30 (-0.60 to 0.00)
-0.25 (-0.70 to 0.00)
Baseline
TG (mmol/L)
Follow-up
△
0.01 (-0.42 to 0.34)
0.18 (-0.23 to 0.55)a
0.28 (-0.23 to 0.93)a
Baseline
LDL-C (mmol/L)
Follow-up
△
-0.42 (-0.80 to -0.01)
-0.26 (-0.76 to 0.14)
-0.19 (-0.77 to 0.41)a
Baseline
Creatinine (μmol/L)
Follow-up
△
1.80 (-0.10 to 3.80)
6.40 (4.80 to 7.80)a
10.50 (7.65 to 16.28)ab
Baseline
eGFR (mL/min/1.73 m2)
Follow-up
△
-2.66 (-3.89 to -1.30)
-7.30 (-8.47 to -5.92)a
-14.45 (-18.29 to -11.10)ab
Baseline
69 (73.4%)
71 (74.7%)
70 (74.5%)
Overweight/obesity (, %)
Follow-up
51(54.3%)
63 (66.3%)
63 (67.0%)
△
-18 (19.1%)
-8 (8.4%)a
-7 (7.4%)a
Baseline
59 (62.8%)
64 (67.4%)
58 (61.7%)
Hypertension (, %)
Follow-up
41 (43.6%)
37 (38.9%)
39 (41.5%)
△
-18 (19.1%)
-27 (28.4%)
-19 (20.2%)
Baseline
71 (75.5%)
79 (83.2%)
79 (84.0%)
Poor glycemic control (, %)
Follow-up
43 (45.7%)
50 (52.6%)
49 (52.1%)
△
-28 (29.8%)
-29 (30.5%)
-30 (31.9%)
Baseline
41 (43.6%)
45 (47.4%)
51 (54.3%)
High TG (, %)
Follow-up
41 (43.6%)
54 (56.8%)
63 (67.0%)a
△
0 (0.0%)
9 (9.5%)a
12 (12.8%)a
Baseline
19 (20.2%)
21 (22.1%)
24 (25.5%)
Low HDL-C (, %)
Follow-up
42 (44.7%)
47 (49.5%)
47 (50.0%)
△
23 (24.5%)
26 (27.4%)
23 (24.5%)
Baseline
85 (90.4%)
79 (83.2%)
79 (84.0%)
Out of target for LDL-C (, %)
Follow-up
67 (71.3%)
68 (71.6%)
73 (77.7%)
△
-18 (19.1%)
-11 (11.6%)
-6 (6.4%)a
Data are or number (%). BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FBG: fasting blood glucose; PBG: postprandial blood glucose; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; eGFR: estimated glomerular filtration rate.
