Research Article

Association of Maternal Diabetes Mellitus and Polymorphisms of the NKX2.5 Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study

Table 2

Univariate analysis of maternal DM and offspring CHD.

Maternal DMControl group ()Case group ()Univariable analysisUnadjusted OR (95% CI)

GDM during this pregnancy
 No592 (95.5%)552 (89.0%); 1
 Yes28 (4.5%)68 (11.0%)2.61 (1.65-4.11)
GDM during previous pregnancy experience
 No595 (96.0%)550 (88.7%); 1
 Yes25 (4.0%)70 (11.3%)3.03 (1.89-4.85)
PGDM in the 3 months before this pregnancy
 No603 (97.3%)557 (89.8%); 1
 Yes17 (2.7%)63 (10.2%)4.01 (2.32-6.94)

DM: diabetes mellitus; CHD: congenital heart disease; GDM: gestational diabetes mellitus; PGDM: pregestational diabetes mellitus; OR: odds ratio; CI: confidence interval. Statistically significant ().