Research Article

Differential HLA Association of GAD65 and IA2 Autoantibodies in North Indian Type 1 Diabetes Patients

Table 1

Demographic details of 252 type 1 diabetes patients from North India.

PhenotypeAll T1D subjectsGADAIA2AGADA+ and
IA2A+
Either GADA+
or IA2A+
PositivesNegativesPositivesNegatives

(%)252128 (50.79)124 (49.21)40 (15.87)212 (84.13)22 (8.73)146 (57.94)

Age at onset (years)
Median (range)12 (6 m-35)12 (6 m-35)12 (3-31)11.5 (3-32)12 (6 m -35)11 (6 m-25)12 (6 m-35)

Age at sampling (years)
Median (range)21 (2-53)21 (2-52)20 (5-49)18 (3-25)21 (2-53)20 (2-35)21 (2-52)

Duration (years)
Median (range)6 (1 m-32)6 (1 m-30)6 (1-32)5.5 (1 m-21)6 (1-32)5 (1 m-17)6 (1 m-30)

Sex
Male, (%)133 (52.78)68 (53.12)65 (52.42)25 (62.5)108 (50.94)14 (63.6)80 (54.8)
Female, (%)119 (47.22)60 (46.88)59 (47.58)15 (37.5)104 (49.06)8 (36.4)66 (45.2)

Abbreviations: : total number of subjects; T1D: type 1 diabetes; m: month(s).