Journal of Diabetes Research / 2021 / Article / Tab 1 / Research Article
Association of the Ratio of Triglycerides to High-Density Lipoprotein Cholesterol Levels with the Risk of Type 2 Diabetes: A Retrospective Cohort Study in Beijing Table 1 Baseline characteristics of the participants in the REACTION study according to serum TG/HDL-C.
Variable All participants TG/HDL-C P valueQ1 (1558) Q2 (1557) Q3 (1560) Q4 (1557) Q5 (1559) Age (years) Male 2613 (33.54%) 419 (26.89%) 493 (31.66%) 504 (32.31%) 591 (37.96%) 606 (38.87%) <0.01 TG/HDL-C SBP (mmHg) DBP (mmHg) Heart rate Height (kg) Weight (cm) BMI (kg/m2 ) WC (cm) HC (cm) ALT (U/L) 18.30 (14.20-24.70) 15.90 (12.80, 20.70) 17.10 (13.30, 22.60) 18.50 (14.60, 24.40) 19.50 (15.20, 27.10) 21.00 (16.30, 28.70) <0.01 AST (U/L) 19.60 (16.70-23.20) 19.50 (16.90-22.40) 19.30 (16.50-22.80) 19.80 (16.90-23.40) 19.70 (16.80-23.70) 19.80 (16.80-23.60) 0.051 Cr (mmol/L) TC (mmol/L) TG (mmol/L) HDL-C (mmol/L) LDL-C (mmol/L) FPG HbA1C (%) Hypertension 2167 (27.82%) 307 (19.72%) 401 (25.75%) 432 (27.69%) 494 (31.73%) 533 (34.19%) <0.01 Tumor 156 (2.00%) 22 (1.41%) 34 (2.18%) 34 (2.18%) 26 (1.67%) 40 (2.57%) 0.15 Stroke 189 (2.43%) 23 (1.48%) 34 (2.18%) 43 (2.76%) 39 (2.50%) 50 (3.21%) 0.03 CHD 474 (6.08%) 82 (5.27%) 91 (5.84%) 94 (6.03%) 97 (6.23%) 110 (7.06%) 0.33 Hyperlipidemia 1067 (13.70%) 107 (6.87%) 152 (9.76%) 204 (13.08%) 234 (15.03%) 370 (23.73%) <0.01 Marital status 0.67 Married 7316 (93.92%) 1445 (92.81%) 1465 (94.09%) 1469 (94.17%) 1455 (93.45%) 1482 (95.06%) Unmarried 29 (0.37%) 5 (0.32%) 6 (0.39%) 6 (0.38%) 6 (0.39%) 6 (0.38%) Widowed 262 (3.36%) 65 (4.17%) 48 (3.08%) 53 (3.40%) 54 (3.47%) 42 (2.69%) Divorced 179 (2.30%) 40 (2.57%) 38 (2.44%) 31 (1.99%) 41 (2.63%) 29 (1.86%) Else 4 (0.05%) 2 (0.13%) 0 (0.00%) 1 (0.06%) 1 (0.06%) 0 (0.00%) Education level 0.048 Illiteracy 77 (0.99%) 17 (1.09%) 17 (1.09%) 12 (0.77%) 16 (1.03%) 15 (0.96%) Primary school 370 (4.75%) 68 (4.37%) 94 (6.05%) 79 (5.07%) 72 (4.63%) 57 (3.66%) Junior high school 2547 (32.73%) 456 (29.31%) 496 (31.90%) 535 (34.32%) 525 (33.74%) 535 (34.36%) High school or technical secondary school 3460 (44.46%) 729 (46.85%) 687 (44.18%) 682 (43.75%) 689 (44.28%) 673 (43.22%) College or above 1329 (17.08%) 286 (18.38%) 261 (16.78%) 251 (16.10%) 254 (16.32%) 277 (17.79%) Smoking (%) <0.01 Never 6370 (81.88%) 1358 (87.22%) 1291 (83.18%) 1293 (83.04%) 1226 (78.79%) 1202 (77.15%) Occasionally 169 (2.17%) 27 (1.73%) 32 (2.06%) 33 (2.12%) 40 (2.57%) 37 (2.37%) Frequently 1241 (15.95%) 172 (11.05%) 229 (14.76%) 231 (14.84%) 290 (18.64%) 319 (20.47%) Alcohol intake 0.78 Never 5515 (70.85%) 1120 (71.89%) 1095 (70.46%) 1129 (72.37%) 1083 (69.65%) 1088 (69.88%) Occasionally 1470 (18.88%) 285 (18.29%) 302 (19.43%) 277 (17.76%) 304 (19.55%) 302 (19.40%) Frequently 799 (10.26%) 153 (9.82%) 157 (10.10%) 154 (9.87%) 168 (10.80%) 167 (10.73%) Strenuous activity 0.24 Yes 222 (2.86%) 51 (3.28%) 32 (2.07%) 47 (3.02%) 50 (3.22%) 42 (2.70%) No 7543 (97.14%) 1502 (96.72%) 1517 (97.93%) 1510 (96.98%) 1502 (96.78%) 1512 (97.30%) Walking <0.01 Yes 6742 (86.80%) 1369 (88.15%) 1376 (88.83%) 1336 (85.81%) 1349 (86.92%) 1312 (84.32%) No 1025 (13.20%) 184 (11.85%) 173 (11.17%) 221 (14.19%) 203 (13.08%) 244 (15.68%) Family history of T2DM 1916 (24.61%) 363 (23.30%) 381 (24.49%) 373 (23.96%) 374 (24.04%) 425 (27.28%) 0.09 Family history of tumors 1655 (21.26%) 340 (21.82%) 319 (20.50%) 325 (20.87%) 340 (21.85%) 331 (21.25%) 0.86
TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; WC: waist circumference; HC: hip circumference; ALT: alanine aminotransferase; AST: aspartate aminotransferase; Cr: creatinine; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; FPG: fasting plasma glucose; HbA1c: hemoglobin A1c; CHD: coronary heart disease.
