Investigation of the Mechanism of Complement System in Diabetic Nephropathy via Bioinformatics Analysis

Table 1

The most significant clusters of common DEGs.

Cluster	Network	Nodes	Edges	Score	Cluster genes
1		21	203	20.3	EVI2A, RNASE6, LAPTM5, LYZ, CD53, CLEC10A, TYROBP, DOCK2, ALOX5, IL10RA, C1QA, MS4A6A, CD52, C1QB, ITGB2, MS4A4A, CD48, CD163, VSIG4, CYBB, IRF8
2		13	62	10.3	TGFBI, VCAN, THBS2, CFB, CLU, COL1A2, IGFBP3, COL6A3, LUM, KRT19, TNC, PROM1, TAGLN
3		7	21	7	CD44, ALB, FN1, CCL5, SERPINF1, IGF1, C3

The red nodes display the core genes of the cluster; the green nodes represent the normal cluster genes. Furthermore, the density of lines among different nodes shows the interaction relationship between cluster genes.