Association of HLA-B Gene Polymorphisms with Type 2 Diabetes in Pashtun Ethnic Population of Khyber Pakhtunkhwa, Pakistan

Table 5

Association between selected 5 single-nucleotide polymorphisms and T2D.

SNP	Chr(gene)	Minor allele	OR	CI (95%)	value
rs2308655	6(HLA-B)	C	2.233	1.233-4.077	0.009
rs1051488	6(HLA-B)	T	1.301	0.745-2.272	0.355
rs1131500	6(HLA-B)	T	1.199	0.687-2.092	0.522
rs1050341	6(HLA-B)	T	0.98	0.562-1.709	0.944
rs1131285	6(HLA-B)	C	1.17	0.537-2.549	0.692
Adjusted odd ratio
rs2308655	6(HLA-B)	C	7.485	2.353-23.812	0.001
rs1051488	6(HLA-B)	T	0.574	0.00-0.010	0.999
rs1131500	6(HLA-B)	T	1.779	0.00-0.003	1
rs1050341	6(HLA-B)	T	0	0.01-0.002	0.999
rs1131285	6(HLA-B)	C	0.484	0.177-1.322	0.157

In binary regression analysis: is considered significant; OR: odd ratio; CI (95%): 95% confidence interval; T2D: type 2 diabetes.