Unique Biomarker Characteristics in Gestational Diabetes Mellitus Identified by LC-MS-Based Metabolic Profiling
Table 1
General characteristics of study subjects.
Characteristic
No GDM
GDM
-value
Age, years
0.001
Age for marriage, years
0.115
Height, cm
0.138
Weight, kg
0.016
BMI, kg/m2
0.001
Weight gain, kg
0.930
BMI before pregnant, kg/m2
0.001
Gravidity
0.149
Parity
Nulliparous
22
16
Multiparous
12
18
0.147
Gestational weeks
0.008
Systolic blood pressure (mm Hg)
0.055
Diastolic blood pressure (mm Hg)
0.420
Fasting glucose (mmol/l)
1 h glucose, OGTT (mmol/l)
2 h glucose, OGTT (mmol/l)
HbA1C (%)
Insulin (μU/ml)
1 h insulin (μU/ml)
0.372
2 h insulin (μU/ml)
0.001
HOMA-IR
Triacylglycerides (mmol/l)
0.001
Total cholesterol (mmol/l)
0.083
LDL-cholesterol (mmol/l)
0.007
HDL-cholesterol (mmol/l)
0.003
ALT, median(range), U/l
0.500
AST, median(range), U/l
0.188
GDM, gestational diabetes mellitus; HbA1c, hemoglobin A1; HOMA-IR, homeostasis model of assessment-insulin resistance; ALT, alanine aminotransferase; AST, aspartate aminotransferase. Data are .-test in continuous variables and chi-square test in categorical data were performed as appropriate. Results were considered significant when , compared with control group.
