The Association of Postprandial Triglyceride Variability with Renal Dysfunction and Microalbuminuria in Patients with Type 2 Diabetic Mellitus: A Retrospective and Observational Study
Table 3
Characteristics of study participants for the secondary analysis with three indices of postprandial TG variability groups ().
Variable
Higher-SD group: ()
Lower-SD group: ()
value
Higher-Adj-SD group: ()
Lower-Adj-SD group: ()
value
Higher-MMD group: ()
Lower-MMD group: ()
value
Age (yr)
67 (60-76)
68 (61-75)
0.3842
67 (60-75)
68 (61-75)
0.2935
67 (60-75)
68 (61-76)
0.1994
Sex (male)
53 (58)
43 (48)
0.1584
52 (58)
44 (48)
0.1531
49 (54)
47 (52)
0.8267
Duration of diabetes (yr)
9 (5-16)
14 (7-19)
0.0287
10 (5-16)
13 (7-19)
0.0460
9 (5-15)
14 (7-19)
0.0075
BMI (kg/m2)
23.7 (22.2-25.7)
23.3 (21.3-24.9)
0.0984
24.0 (22.1-25.8)
23.3 (21.5-24.9)
0.0921
24.0 (22.1-25.8)
23.3 (21.7-24.8)
0.0674
sBP (mmHg)
128 (122-136)
132 (124-138)
0.0616
128 (122-136)
132 (124-138)
0.0894
128 (122-136)
132 (124-138)
0.0357
dBP (mmHg)
74 (70-80)
72 (70-78)
0.4281
74 (70-80)
72 (70-78)
0.4717
76 (70-80)
72 (70-78)
0.3534
eGFR (mL/min/1.73 m2)
75.0 (63.1-88.1)
75.6 (62.3-87.0)
0.8604
75.0 (63.1-88.0)
75.6 (62.2-87.1)
0.8403
75.4 (63.1-88.6)
75.5 (62.3-86.4)
0.7282
s-Cr (mg/dL)
0.73 (0.60-0.87)
0.69 (0.58-0.81)
0.2107
0.73 (0.61-0.87)
0.69 (0.58-0.81)
0.2000
0.71 (0.59-0.87)
0.70 (0.59-0.82)
0.7592
Maximum TG (mg/dL)
270 (212-343)
135 (113-158)
<0.0001
274 (212-343)
136 (114-158)
<0.0001
270 (211-343)
135 (113-158)
<0.0001
Minimum TG (mg/dL)
109 (86-147)
71 (56-96)
<0.0001
109 (86-147)
71 (57-96)
<0.0001
105 (86-147)
72 (56-98)
<0.0001
Mean TG (mg/dL)
181 (144-233)
99 (80-121)
<0.0001
182 (145-234)
99 (80-123)
<0.0001
181 (143-233)
99 (80-126)
<0.0001
SD
53 (45-80)
24 (17-27)
<0.0001
54 (46-80)
24 (17-28)
<0.0001
53 (45-80)
24 (17-27)
<0.0001
Adj-SD
49 (41-73)
22 (16-25)
<0.0001
49 (41-73)
22 (16-26)
<0.0001
49 (41-73)
22 (16-25)
<0.0001
MMD
144 (115-209)
58 (44-70)
<0.0001
146 (116-210)
58 (45-70)
<0.0001
144 (115-209)
58 (44-70)
<0.0001
HDL-C (mg/dL)
50 (43-60)
60 (49-69)
0.0004
50 (43-59)
60 (49-69)
0.0004
51 (45-61)
59 (47-68)
0.0117
LDL-C (mg/dL)
98 (86-118)
95 (83-115)
0.4922
98 (86-116)
95 (83-115)
0.5231
98 (85-115)
96 (83-117)
0.9604
HbA1c (%)
6.8 (6.4-7.4)
6.6 (6.3-7.0)
0.1717
6.8 (6.4-7.4)
6.7 (6.3-7.0)
0.1907
6.8 (6.4-7.4)
6.7 (6.3-7.1)
0.3632
Smoking (current, past, never)
16 (18), 34 (37), 41 (45)
9 (10), 24 (27), 57 (63)
0.0430
16 (18), 33 (37), 40 (45)
9 (10), 25 (27), 58 (63)
0.0424
15 (16), 33 (36), 43 (47)
10 (11), 25 (28), 55 (61)
0.1680
Albuminuria (mg/dL)
10.6 (6.5-16.5)
8.4 (5.2-14.1)
0.1523
10.6 (6.3-16.6)
8.5 (5.3-14.0)
0.1727
10.6 (6.7-16.5)
8.4 (5.1-13.9)
0.0958
Statins intake
50 (55)
49 (54)
0.9461
49 (55)
50 (54)
0.9238
52 (57)
47 (52)
0.5061
Fibrates intake
5 (5)
0 (0)
0.0241
5 (6)
0 (0)
0.0211
5 (5)
0 (0)
0.0241
Cholesterol transport inhibitors intake
10 (11)
3 (3)
0.0461
10 (11)
3 (3)
0.0378
10 (11)
3 (3)
0.0461
TG: triglyceride; SD: standard deviation; Adj-SD: adjusted SD; MMD: maximum minus minimum difference; BMI: body mass index; sBP: systolic blood pressure; dBP: diastolic blood pressure; eGFR: estimated glomerular filtration rate; s-Cr: serum creatinine; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HbA1c: glycated hemoglobin; maximum TG: the highest value of postprandial TG between 2012 and 2015; minimum TG: the lowest value of postprandial TG between 2012 and 2015. Mann–Whitney test. Pearson’s chi-square test categorical variables are presented as (%), and continuous data are represented as median (interquartile range).
