Identification of Flavonoid C-Glycosides as Promising Antidiabetics Targeting Protein Tyrosine Phosphatase 1B

Table 2

Thermodynamic binding free energy component for flavonoid C-glycosides towards PTP1B.

Energy components (kcal/mol)
Complexes
PTP1B + ursolic acid
PTP1B + vitexin
PTP1B + apigenin
PTP1B + orientin

PTP1B: protein tyrosine phosphatase 1B; : van der Waals energy; : electrostatic energy; : gas-phase free energy; : solvation free energy; : total binding free energy.