Comparison of Risk Assessment Strategies for Patients with Diabetes Mellitus and Stable Chest Pain: A Coronary Computed Tomography Angiography Study
Table 2
Characteristics by risk groups based on the NICE and ESC strategy.
Total
NICE strategy
ESC strategy
Low
High
Low
High
Age (years, )
<0.0001
<0.0001
Female
331 (55)
128 (49)
203 (60)
0.0078
101 (43)
230 (63)
<0.0001
Hypertension
409 (68)
172 (65)
237 (70)
0.2763
143 (60)
266 (73)
0.0017
Hyperlipidemia
313 (52)
130 (49)
183 (54)
0.3045
109 (46)
204 (56)
0.0219
Smoking
284 (47)
111 (42)
173 (51)
0.0385
91 (38)
193 (53)
0.0007
Abnormal ECG
259 (43)
0 (0)
259 (76)
<0.0001
95 (40)
164 (45)
0.2760
Symptom
<0.0001
0.0001
Nonanginal chest pain
284 (47)
263 (100)
21 (6)
91 (38)
193 (53)
Atypical angina
239 (40)
0 (0)
239 (71)
100 (42)
139 (38)
Typical angina
79 (13)
0 (0)
79 (23)
46 (20)
33 (9)
Obstructive CADb
271 (45)
65 (25)
206 (61)
<0.0001
12 (5)
259 (71)
<0.0001
MACE
45 (7)
13 (5)
32 (9)
0.0422
6 (3)
39 (10)
0.0001
Cardiac death
11 (2)
2 (1)
9 (3)
0.1244
0 (0)
11 (3)
0.0044
Nonfatal MI
34 (5)
11 (4)
23 (6)
0.2325
6 (3)
28 (7)
0.0067
SD: standard deviation; CAD: coronary artery disease; NICE strategy: 2016 National Institute of Health and Care Excellence guideline-determined risk assessment strategy; ESC strategy: 2019 European Society of Cardiology guideline-determined risk assessment strategy; ECG: electrocardiogram; MI: myocardial infarction; MACE: major adverse cardiovascular events. Values are presented as (%) unless stated otherwise.