Diabetes represents an emerging global epidemic and one of the leading causes of morbidity and mortality. Its insidious and chronic nature often increases the threat posed. Diabetes has been justly labelled as the “silent epidemic.” It is estimated that approximately 425 million people had diabetes in 2017 worldwide and, by 2045, this number is expected to rise to 629 million.

Complications of diabetes are very common and may even present at diagnosis. They affect various parts and functions of the human body, leading to disability, reduced quality of life, and death. Traditionally, diabetic complications are classified as macro- and microvascular. Macrovascular complications include coronary artery disease, peripheral arterial disease, and stroke, while microvascular complications include diabetic nephropathy, neuropathy, and retinopathy.

Given the increasing number of patients with diabetic complications worldwide, there is no doubt that a better understanding of these complications, including the underlying mechanisms, is very important and might contribute to new treatment options.

We would like to invite investigators to submit original research articles or review articles that will improve our understanding of the diagnosis, pathogenesis (including novel molecular mechanisms), pathophysiology, treatment, and prognosis of these complications.

Potential topics include but are not limited to the following:

• The diagnosis, pathogenesis, and clinical management of diabetic foot, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, peripheral arterial disease, coronary heart disease, stroke, vascular damage and endothelial dysfunction, infections in patients with diabetes, and intestinal and liver complications due to diabetes
• The diagnosis and evaluation of treatment efficacy
• Advances in molecular genetics and molecular diagnostics
• New insights into treatment