Abstract

The study of heat conduction phenomena using peridynamic (PD) theory has a paramount significance on the development of computational heat transfer. This is because PD theory has got an interesting feature to deal with the inherent nonlocal nature of heat transfer processes. Since the revolutionary work on PD theory by Silling (2000), extensive investigations have been devoted to PD theory. This paper provides a survey on the recent developments of PD theory mainly focusing on diffusion based peridynamic (PD) formulation. Both the bond-based and state-based PD formulations are revisited, and numerical examples of two-dimensional problems are presented.

1. Introduction

Modeling and simulation of diffusion constitute an essential process we usually come across in our everyday life and in a number of industrial processes. The basic and fundamental knowledge of diffusion process is vital in the efficient utilization of energy in different cooling and heating processes. The governing mathematical equations of many physical phenomena in engineering and science are described by local diffusion equations. In solving these equations, researchers employed several numerical techniques in the past several years including finite element method (FEM), boundary element method (BEM) [1], finite difference method (FDM), and meshless methods. At the continuum level, diffusion processes are typically defined by local models via the famous Fourier’s law of heat conduction and Fick’s law of mass transport. The main drawback of the local models is that they ignore the nonlocal effect. In fact, the effect of nonlocality cannot be ignored due to the fact that nonlocality plays a significant role in diffusion processes like heat conduction, moisture flow, electrical conduction, pitting corrosion, and hydraulic fracturing. Hence, it is quite critical to develop a nonlocal model that accommodates both the nonlocality effect and emerging discontinuities at the same time.

In this regard, peridynamics (PD) is a promising and suitable approach for dealing with the aforementioned challenges encountered by the local models. PD theory was proposed by Silling [2]. It was mainly intended to deal with solid mechanics problems, but later it was effectively extended and realized to solve diffusion related problems. An interesting breakthrough that proves that PD is beyond solid mechanics problems was presented by Gerstle et al. [3]. In this article, the authors showed the applicability of PD in solving multiphysics problems like electromigration. The beauty of PD theory is that it takes into account both nonlocal interactions and constitutive laws simultaneously. Later, Bobaru and Duangpanya [4] developed a 1D heat conduction PD formulation, and then they extended it to 2D heat conduction problems with discontinuities [5]. On the other hand, [6] compared and analyzed various discretization schemes of nonlocal diffusion (ND) and linear PD equations by demonstrating illustrative approaches developed for solving nonlocal models with both nonintegrable and integrable kernels. In this article the authors paid attention to conforming finite element and quadrature-based finite difference techniques in the discretization of PD and ND models. Following the pioneering works of Bobaru and Duangpanya [4, 5], Agwai [7] and Oterkus et al. [8] pushed further the bond-based PD formulation developed by [4, 5] to the state-based PD formulation. The formulation developed by [7, 8] is so general and can be reduced to the bond-based formulations of [4, 5]. The only difference between the bond-based formulations in [4, 5, 7, 8] is that they use different response functions (kernel functions) as briefly described by Chen and Bobaru [9].

PD formulation for saturated steady-state pressure driven porous flow has been demonstrated by Katiyar et al. [10]. Later Jabakhanji and Mohtar [11] extended the work of [10] to transient moisture flow in unsaturated, anisotropic, and heterogeneous soils in PD framework. A PD diffusion model by employing Green’s function has been developed by [12]. In this study, the steady-state and transient PD Green’s functions were derived and implemented to 2D infinite plate which is heated by a Gauss source. PD formulation of heat conduction in functionally graded materials (FGMs) has been developed by Liao et al. [13]. The authors in this article employed a state-based peridynamic (PD) approach to simulate heat conduction phenomena with insulated cracks in FGMs. In the same year [14], addressed the issue of transient heat transfer by combining the classical and PD formulations simultaneously. In this study, the integrodifferential equations have been solved by employing the spectral technique based Galerkin scheme. Another contribution in relation to PD diffusion problems by employing a general-purpose finite element analysis software ANSYS was from [15]. The technique implemented in this article was interesting in that it reduced the computational time significantly due to the fact that the authors used implicit time integration scheme.

The transient advection diffusion PD model has been presented by Zhao et al. [16] by extending the bond-based PD approach developed by Bobaru and Duangpanya [5]. Xue et al. [17] on the other hand addressed thermal contact problems by utilizing the state-based version of peridynamic formulation. In this article, the authors employed the domain decomposition technique to solve heat transfer problems by considering the thermal flux and temperature as the primary variables. Recently, [18] applied PD differential operator to study a refined bond-based PD heat conduction model by reviewing the present state-based and bond-based PD heat conduction models. By extending the work of [13], Tan et al. [19] performed their research on heat conduction in FGMs with discontinuities using PD by taking into consideration the effect of surface correction near the crack and domain boundaries. Later, [20] investigated the effects of interfacial transition zone properties and diffusivity on chloride diffusion concrete of arbitrarily distributed aggregates using multiscale PD model. To improve the computational precision and diminish the cost of computation, the authors employed multiscale discretization scheme.

PD diffusion model with a capability of handling unbounded domains using accurate absorbing boundary conditions (ABCs) has been developed by [21]. In this study, the authors employed mesh-free discretization scheme in case of PD diffusion models whereas FEM has been employed in the case of local diffusion models. Wang et al. [22] very recently developed a dual horizon PD formulation to study thermal diffusion problem. The Lagrangian formulation has been implemented in this study to develop the governing equations. One of the benefits of this formulation is that it permits the implementation of flexible discretization in the domain of interest which in turn contributes a lot to the reduction of computational time. Yan et al. [23] further implemented the BB-PD formulation to model a coupled chemical transport and water flow in unsaturated discontinuous and heterogeneous media. In this study, processes like dispersion, diffusion, and advection have been considered in partially saturated porous media.

The main objective of this article is to revisit recent developments in PD applications that are pertinent to diffusion-type problems. Therefore, it is structured as follows. The first section introduces and reviews PD theory in general. The second section is devoted to PD formulation of diffusion-type problems; it is segmented into PD heat conduction, PD electrical conduction, and PD moisture flow. Finally, several illustrative examples of different cases are presented, and the performance of PD is investigated.

2. Review of Peridynamic Theory

Diffusion related PD formulation cannot be understood without understanding its uniqueness as compared with classical continuum theory. In classical continuum mechanics, material particles interact with the nearby immediate material particles as shown in Figure 1(a). In contrast to the classical continuum theory, PD material points are allowed to interact with material points within its family (Hi) at a finite distance called horizon as shown in Figure 1(b).

PD theory is a nonlocal integrodifferential mesh-free method without spatial derivatives [2, 24]. It is just the nonlocal version of classical continuum theory; its formulation mainly depends on an integrodifferential equation unlike the classical counterpart, which is based on spatial derivatives [24, 25]. The term peridynamics was originally coined by Silling [2] at Sandia National Laboratories in the late nineties. This paper reformulated the continuum based equation of motion (EOM) to integrodifferential equation to deal with spontaneous emergence and propagation of discontinuity in solids. For the PD formulation of elasticity, consider a body having a region Ω as shown in Figure 2. With reference to Figure 1, the EOM for particle at time t as proposed in [2] is given as (1). The original formulation in this paper [2] was the bond-based PD theory, where internal forces in a body are modeled as a network of pairwise interactions. The material points interact in a pairwise manner and are restricted to a specified neighborhood through a bond. The force of interaction between a pair of material points is dependent on the deformation of the two points only.where is mass density, is displacement vector field, is pairwise force function (the force vector per unit square of volume that the material point exerts on material point ), is a body force density, is a neighborhood of particle with radius as shown in Figure 2, is the position vector of the nearest particle pointing to from , and is the differential volume of inside the horizon of .

Since its introduction, PD theory has been used to solve a variety of problems. Accordingly, literature concerning peridynamic theory is quite exhaustive and abundant. In the past two decades, several peridynamic studies pertaining to elastic deformation and fracture solids [2, 2628], brittle fracture [2933], fatigue failure [3449], and PD application of damage in composites [33, 43, 5065] have been reported. Studies related to crack initiation and propagation using peridynamics can be found in [30, 6669]. As far as studies related to plasticity, viscoelasticity, and viscoplasticity are concerned, the reader is advised to refer to [7081]. Figure 3 shows the general trend in the number of articles published in the referenced journals. Figure 4 on the other hand shows the citation history of the first pioneering article [2] in the area of PD theory since its first publication. It is evident from these two figures (Figures 3 and 4) that year after year research outputs pertinent to PD theory increase incredibly.

Therefore, the aim of this section is to provide an overview on the computational aspects of PD theory with emphasis on the modeling of diffusion problems. In this regard, the citation trends of the most influential and pioneering articles in the areas of PD based diffusion models are presented as shown in Figure 5 [4, 8]. Figure 5 compared citation trends of the bond-based PD thermal diffusion developed by [4, 5] and state-based PD thermal diffusion formulation of [8]. Similar observations may be realized from Figure 5 too.

Therefore, this section is outlined as follows: the first part provides a review of the state-based PD formulation of heat conduction, followed by electrical conduction and moisture flow. The discussion in this paper mainly revisits the state-based peridynamic theory, and then later we will reduce the SB equations to bond-based (BB) equations as the particular case of state-based peridynamic theory. Although the nonlocal model we propose in this review offers a better predictive capability of high strain gradient and fracture mechanics, the scope of this review is limited to diffusion based problems only.

2.1. State-Based PD Formulation for Heat Conduction

In general, heat transfer is directly related to temperature whether it is radiation, convection, or conduction. Heat conduction is the process by which temperature gradient exists within a body; hence, its primary objective is to determine temperature distribution and exchange of energy within a body. The development of numerical solutions for heat conduction problems is growing as an effective tool in thermal engineering. The applicability of continuum based heat transfer equations to bodies with discontinuities is mathematically awkward due to the fact that these equations contain temperature gradients. To deal with the aforementioned challenges and limitations of the continuum based heat transfer equations, PD theory gives ideal solution. This section covers PD formulation of heat conduction equations. The PD heat conduction equations used in this article are simple and interesting in that thermal conductivity coefficient of a particle is defined within its neighborhood at a certain finite distance called horizon [9], unlike continuum based Fourier theory where a particle interacts only with its immediate vicinity. Hence, PD is a valuable tool that takes into account both the nonlocality effect and discontinuities concurrently across the temperature and other potential fields like electric potential, hydraulic potential, and chemical potential.

The present section addresses studies that are pertinent to heat transfer. Gerstle et al. [3] were the first to propose the analytical and computational simulation of electromigration that accounts for heat transfer in a one-dimensional problem. Later, Bobaru and Duangpanya [4] introduced the bond-based PD formulation for thermal problems with evolving discontinuities. The authors used a constructive approach to obtain the PD equations for heat transfer. Following their previous contribution [4], Bobaru and Duangpanya [5] proposed a multidimensional PD formulation to solve two-dimensional heat conduction problems with discontinuities. Recently, the generalized state-based PD heat transfer problem using Lagrangian approach was demonstrated by Oterkus et al. [8]. In this work, the authors determined the PD material parameter, the micro conductivity, by simplifying the state-based PD heat transfer equation to its bond-based PD heat transfer equation. The authors also confirmed that the governing equation represented the conservation of thermal energy. Later, Chen and Bobaru [9] analyzed the behavior of PD solutions for transient heat diffusion model and studied the convergence properties of the one point Gauss quadrature scheme.

In PD heat conduction, the interaction among material points is due to the exchange of heat. Hence, we present the governing PD equations based on the one proposed by Oterkus et al. [8] and Agwai [7] for the sake of completeness by considering temperature as primary variable.

Based on the generalized state-based PD formulation, the temperature state that contains the temperature difference associated with each interaction of a particular material point is given bywhere is the temperature. Note that states are represented by variables with underscores, and the angular brackets indicate the bond being operated on.

According to [7, 8], the SBPD heat flow state is written as

Therefore, the transient form of heat conduction in the framework of SBPD is expressed as [7, 8]where .

Therefore, (4) may be modified as follows:where is the heat sink or source, is the classical heat flux, and is the specific heat capacity.

For PD heat conduction phenomena, the discrete form of (5) may be expressed in the form of finite sum as follows:where is shape tensor related to thermal field and it is given as follows:where and .

2.1.1. Correlations between the Classical Heat Flux and PD Heat Flow State

The heat flow scalar state contains the heat flow densities associated with all the interactions [7, 8]. Therefore, heat flow density has units of heat flow rate per volume square.

Equation (9) resembles the divergence of heat flux , which has units of heat flow rate per volume and is given in the above equation.

Therefore, the PD heat flow state can be correlated to the heat flux . Then, the expression that relates the heat flux to the heat flow state has been borrowed from [7, 8].

2.1.2. Bond-Based Peridynamic (PD) Heat Conduction Formulation

In a bond-based peridynamic model, material point can interact with all neighboring material points in its horizon in a pairwise manner. The change in temperature at the two end points of a bond is assumed to cause the heat to flow along the central axis of the bond only. When material points interact in a pairwise manner and are restricted to a specified neighborhood through a bond, eq (6) may be reduced as follows:where is micro conductivity of the connected thermal bonds that joins point i and j as shown in Figure 2, is the horizon volume of material point centered at , and is the PD conductivity of thermal bonds between material points and .

2.1.3. Linking Peridynamic Properties with Those of the Classical Counterparts

In order to create a relationship between the PD properties and the standard material properties, we borrow directly expressions from [8]. Thus, for one-, two-, and three-dimensional analysis, the PD thermal micro conductivities are expressed correspondingly aswhere , and are horizon, cross-sectional area, thermal conductivity, and thickness, respectively.

2.2. State-Based PD Formulation for Electrical Conduction

The present section deals with the PD formulation of electrical conduction. Articles that are pertinent to electrical conduction phenomena alone are quite limited, but there are few about the coupled form. The application of PD to the failure of dielectric solids can be found in [82]. On the other hand, Prakash and Seidel [83] explained the effectiveness of PD model in examining the piezoresistive composite materials. The same authors further developed an electromechanical PD model to predict the deformation and damage of explosive materials [84, 85]. Zeleke et al. [8688] on the other hand developed a PD formulation for thermoelectric phenomena. A recent contribution of Diana and Carvell [89] employed micropolar PD (MPPD) model to solve electromechanical problems. Very recently, Zeleke et al. [88] employed PD theory to study discontinuities in electric and thermal fields.

Therefore, in this section, we first describe PD electrical conduction using the generalized state-based approach. The derivation of the generalized PD electrical conduction equation is established, and the peridynamic variables are elucidated. Afterward, simplifications are made, so that the bond-based PD formulation for electrical conduction could be developed.

For electrical conduction phenomena, material points exchange electrical current with points inside its neighborhood defined by the horizon. In this section, we derived the state-based PD electrical conduction equation by employing a variational technique like Katiyar et al. [10] for pressure driven porous flow. Based on state-based PD formulation, the potential state that comprises the electrical potential difference linked with each interaction of a particular material point is given bywhere is the electric potential.

Therefore, the governing equation for electrical conduction in the framework of SBPD is obtained aswhere is the electrical current flow state, is the time rate of charge density, and is the charge source. By extending the SBPD heat flow state, we can write the state-based current flow state aswhere is PD electrical potential scalar state and is current flow state; .where is classical current flux and is charge source.

Equation (18) in its discrete form may be written aswhere is shape tensor related to electrical field and it is given as follows:

2.2.1. Relationship between Electrical Current Density and PD Current Flow State

The current flow scalar state comprises the current flow densities linked with all the participating material points having units of current flow per unit volume square and given as

Equation (22) resembles the divergence of electric flux , which has units of charge flow rate per volume and is given as

By extending the PD heat flow state formulation to the current flow state, we may have the expression that relates the current flux to the current flow state as follows:

2.2.2. Bond-Based Peridynamic (PD) Electrical Conduction Formulation

In a bond-based peridynamic model, material point can interact with all neighboring material points in its horizon in a pairwise manner. The change in electric potential at the two points of a bond is assumed to cause the electric current to flow along the axis of the bond only, which results in pairwise interaction of material points. Therefore, (19) may be reduced as follows:where is micro conductivity of the associated electrical bonds that connect points i and j as shown in Figure 2, is the horizon volume of material point centered at , and is the PD conductivity of electrical bonds between material points and .

2.2.3. Linking Peridynamic Properties with Those of the Classical Counterparts

In order to create a connection between the PD properties and the classical material properties, we directly borrow expressions from [8] and extend them to electric field. Thus, for one-, two-, and three-dimensional analysis, the PD electrical micro conductivities are expressed as follows:where , and are horizon, cross-sectional area, electrical conductivity, and thickness, respectively.

2.3. State-Based PD Formulation for Chemical and Water Transport

In this section, the PD models of chemical transport and water flow in their uncoupled state were revisited. In the realm of PD theory, a number of scholars addressed the issue of diffusion processes in both saturated and unsaturated porous media. Katiyar et al. [10] established a PD model to study the steady-state water flow in saturated porous media by taking into account the effect of heterogeneities and discontinuities. Later, Jabakhanji and Mohtar [11] addressed the transient nature of moisture flow in unsaturated porous media in PD framework. Very recently, [23] employed PD theory to simulate a coupled chemical transport and water flow. In this study, the authors implemented the BB-PD theory to formulate chemical transport and water flow by taking into account diffusion, advection, and dispersion processes in partially saturated porous media.

2.3.1. Chemical Transport in the Realm of PD

Similar to the water flow due to gravity and heat flow due to temperature gradient, diffusion of chemicals moves from high to low potential. Therefore, we can describe Fick’s law in PD framework for chemical transport in a similar way to what we did for PD based Fourier's equation of heat diffusion.where

The discrete form of (29) may be written aswhere is the flux of solute, D is the diffusivity of solute in solvent, C is the concentration of solute, and is the rate of generation of solute per unit volume of the solvent.

2.3.2. Bond-Based Peridynamic (PD) Chemical Transport

In a bond-based PD model, point interacts with neighboring material points in its domain in a pairwise manner. The change in chemical concentration at the two end points of a bond is assumed to cause the chemical to flow along the axis of the bond only. The pairwise interaction of material points is written as follows:

The response function of diffusion is designated by and expressed aswhere is micro diffusivity of the associated chemical bonds that connect points i and j as shown in Figure 2, is the horizon volume of material point centered at , and is the PD diffusivity of chemical bonds between material points and .

In order to create a linkage between the PD properties and the classical material properties, we directly borrow expressions from [8] and coined them as chemical transport phenomena. Thus, for one-, two-, and three-dimensional analysis, the PD micro diffusivities are expressed, respectively, as follows: d is defined in terms of the classical diffusivity D aswhere , and are cross-sectional area, thickness, diffusivity of solute, and horizon, respectively.

For the examples that follow, the PD heat conduction equation has been solved numerically by replacing the nonlocal integral equation (11) with finite sum:where n signifies the number of time steps, denotes the point of interest, and is the point in the horizon of . is the volume subdomain related to the material point . The forward difference computational scheme has been employed by solving the following equation:

3. Case Studies

In this section, we implemented the state-based PD approach to illustrate the versatility of the PD formulation. Five illustrative examples are simulated and presented; the first example illustrates two-dimensional heat conduction with symmetric boundary condition. The effect of nonsymmetrical boundary condition is exemplified in the second example. The third and fourth examples demonstrate the beauty of PD theory in dealing with discontinuities. Finally, a single pellet of thermoelectric material has been considered to compute the temperature and voltage values.

Example 1. In this example, square plate with its dimensions that are shown in Figure 6 and material properties that are shown in Table 1 has been considered. The plate is subjected to the following symmetric boundary and initial conditions:
Boundary conditions:Initial conditions:The domain in this demonstrating example is discretized into 20 by 20 nodal points in the x and the y directions, respectively, with time step of . Figure 7 illustrates PD and FEM comparisons of two-dimensional temperature variations. As presented in Figure 7, the temperature decreases with time and reaches its steady-state value. Further, it is found that PD results are in close agreement with those of FEM counterpart.
From Figure 8, we also noticed a decrease in temperature inside the plate as the time goes by. The temperature in the plate was initially , and was imposed at the bottom and top boundaries. Figure 8 illustrates the temperature contour plot for time t = 10 s, t = 20 s, 40 s, 60 s, 80 s, and 100 s.

Example 2. Heat conduction with nonsymmetric boundary.
In this example, a temperature of 0°C was enforced at the bottom of the plate and 300°C at the top, and the temperature on the rest of the plate was subjected to initial value of 100°C as shown below:
Initial conditions:Boundary conditions:The temperature field across the plate is illustrated in Figure 9. The temperature distribution inside the plate becomes closer to linear distribution as simulation time increases. In this example, we also compared temperature values from PD and FEM at t = 100 s. As can be seen from Figure 9, temperature distributions tend to be interestingly closer. Further, Figure 10 depicts the temperature contour of the plate up to 100-second simulation time. Therefore, from the above two examples, we may draw the conclusion that PD theory is an interesting theory that can deal with diffusion problems correctly.

Example 3. Adiabatic crack with constant heat flux perpendicular to crack surface.
To validate the proposed PD method in handling discontinuities, we considered here an inclined crack with adiabatic inclined crack as shown in Figure 11. In this example, the dimensions are the same as the previous examples and β = 45°. Equal and opposite magnitude of temperature has been imposed on the top and bottom edge of the plate in order to keep the heat flux constant. In the meantime, the left and right edges of the plate are heat-insulated. The inclined crack is modeled as an adiabatic crack in order to capture the discontinuity in temperature profile using PD theory as shown in Figure 12.
Figure 12 depicts the comparison between PD results and FEM in the case of adiabatic inclined crack. Figure 12 proves that our PD solution agrees well with the solution from FEM. Hence, our proposed peridynamic model is able to capture the transient heat conduction of a plate with an insulated inclined crack.
Further, Figure 13 illustrates the PD and FEM temperature variations along the Y-axis for t = 100 s. As we can see from Figure 13, PD and FEM results are in close agreement.

Example 4. Isothermal crack with specified temperature at the crack surface.
This example considers an inclined crack with isothermal crack condition as shown in Figure 14. Once again, the dimensions are the same as the previous examples and β = 45°. Here, the temperature values of equal magnitude are specified at the four edges of the plate, and an essential boundary condition is defined on the crack surface. For this set of boundaries, we choose .
Similar to Example 3, we compared our PD results with those of FEM. It is also observed from Figures 15 and 16 that our solution is consistent with solution from FEM.

Example 5. Single pellet of bismuth telluride .
The main target of this example is to show the effectiveness of PD theory in dealing with couple fields. A comparison between PD solution and results from literature [90] has been considered by taking into account constant material properties and temperature dependent material properties of bismuth telluride (Bi2Te3).

Case 1. Constant material properties.
Material properties and model geometry are given in Table 2 and Figure 17 [90], respectively. The problem considered in this example is enforced as one-dimensional linear problem [90].
Temperature and voltage boundary conditions are enforced asConsidering constant material properties, temperature results from PD simulation have been obtained and compared with results from [90] as depicted in Figure 18. From Figure 18, it is observed that PD results quite agree with those from [90].
A further study on electric potential values using PD has been conducted. Simulation results from PD and those of from [90] have been compared in Figure 19. It is clear from Figure 19 that our PD results agreed well with those from [90].

Case 2. Temperature dependence of material properties.
Table 3 depicts the dimensions of model geometry and material properties [90]. Similar to Case 1, temperature and electric potential values have been computed using PD. Boundary conditions and dimensions are similar to Case 1.
Here, we also made a comparison between PD temperature values and those from [90]. As can be seen from Figure 20, PD results smoothly agree with those from [90].
Temperature dependent electric potential values using PD have been computed and compared with results from [90]. It is quite evident from Figure 21 that PD results agree very well with those from [90].

4. Conclusion

This article revisited the PD computational scheme that is pertinent to diffusion based problems like heat diffusion, electrical conduction, and chemical transport. In this review, PD functional integrals play a vital role in replacing gradients of hydraulic potentials, solute concentration, temperature, and electrical conduction. This is because functional integrals are valid anywhere in the domain despite the presence of discontinuities. Here, the state-based PD diffusion equation developed by [7, 8] has been borrowed to write electrical conduction and chemical transport equations. Five examples have been demonstrated to show the versatility of the PD theory, and the results were compared with results from [90] and FEM. Temperature values inside a square plate have been determined in the first example by considering symmetric temperature boundary. In the second example, nonsymmetric temperature boundary has been considered, and results were presented. In both examples, the PD results have been compared with FEM results, and close agreement has been obtained. In the third and fourth demonstrations, we proved the competence of PD in handling discontinuities. In these examples, results from PD and FEM have been also compared and found to be interesting. Finally, we solved one-dimensional thermoelectric phenomenon by comparing PD results with those from [90] and proved the capability of PD to take care of coupled fields. Hence, we may conclude that PD theory is way beyond solving fracture and solid mechanics problems. It is also versatile in dealing with diffusion based models and their coupled fields.

Conflicts of Interest

The authors wish to confirm that there are no known conflicts of interest associated with this publication.