Review Article

Sources of Indoor Air Pollution and Respiratory Health in Preschool Children

Table 3

Studies analyzing the relationship between the use of solid fuels, biomass, fuel oil, and kerosene in the home and the respiratory health of children under the age of 5.

Location
Year
Author
DesignSample population:
Age
Number of cases
Disease studiedExposureControl variablesResults: adjusted OR/RR (IC 95%)
Definition of the caseInformation sourceSource, chemical productsEvaluationLevels (% exposure)

Studies conducted in Africa and Asia

2 suburbs of Delhi: Kusumpur Pahari and Kathpulty
1998
Sharma et al. [17]
Case-control prospective633 children
(320 1year of age)
- 316 Kathapulty
- 317 Kusumpur
Acute lower respiratory tract infection (ALRTI)Qwood keroseneKathapulty: 45%  W 55%  K
Kusumpur: 55% W 45% K
- Job, parents’ educational level
- Homes with 1bedroom, location of kitchen,
- Family size
- Siblings
There were 3 children with three episodes of acute lower respiratory tract infections in the wood group as compared to the kerosene group, but in the latter, there was a tendency to cook inside the home in the presence of the children.

Northern India
2001
Broor et al. [18]
Case-control512 children under the age of 5Severe acute lower respiratory tract infection.
Cases (201):
admitted to hospital
Controls (311):
healthy children attended to in the same hospital’s pediatric outpatient clinic.
Survey (parents)Use of fuel other than liquid petroleum gas for cooking: biomass, wood, harvest waste, dungQuestionnaire (parents)36.8% of the cases and 20.6% of the controls used a cooking fuel other than liquid petroleum gas.- Parents: age, education
- Smoking
- Type of house: semi-attached with foundation
- Children: breastfed, vaccinated
OR for ALRTI associated with the use of cooking fuel other than liquid petroleum gas.
2.51 (1.51–4.16)

Calcutta
2002
Mahalanabis et al. [19]
Case-control2–35 months
Cases: 127
Controls: 135
Pneumonia
Cases: hospital admission with pneumonia
Controls: from an outpatient immunization clinic
Hospital registers
Hospital diagnosis of pneumonia
Use of solid fuelQ- Mother’s education
- Economic status (televisions, electric fans  )
- Number of siblings, large animals
- Child: nutrition, history of asthma
Use of solid fuel
OR: 3.97 (2:00–7.88)

India
2005
Mishra [14]
Transversal29,768 children
0–35 months
Acute respiratory infection (ARI) (coughing with tachypnea in the two weeks prior to the survey)Children selected in a national health survey (National Family Health Survey NFHS-2)(ídem)QHighly pollutantCovariables added: status of the head of family, type of house, separate kitchen or not, agglomeration of people ( 3 people per room or >3).- Highly pollutant fuels: 1.82 (1.58–2.09)
- After adjusting for various covariables:
1.58 (1.28–1.95)
- In homes where both biomass and cleaner fuels were used
1.41 (1.17–1.70)
- Boys/girls:
1.12 (1.01–1.23)

Suburbs of Bangladesh (Dhaka)
2007
Khalequzzaman et al. [20]
Case-control116 Children under the age of 5
65 biomass
51 solid fuel
During the previous month
Prevalence of symptoms and signs:
Reddening and itching of eyes, itchy skin, nasal congestion, cough, shortness of breath, intercostal muscle retraction, wheezing, sore throat
Prevalence of illness:
Respiratory problems, bronchiolitis, asthma, pneumonia
Eczema, diarrhea, viral fever
Q and examination of symptomsIndoor air concentrations of VOCs, CO, CO2, NO2 and dust particles.Biomass 53%
Fossil fuel 47%
- Mother’s age, educational level and job
- Smoking in the house by care-taker
- Family income, cost of fuel
-Ventilation
Use of biomass versus fossil fuels
- Cough 1.9 (0.6–6.3)
- Shortness of breath 6.3 (1.6–29.1)
- Intercostal muscle retraction 5.5 (1.3–29.4); wheezing 4 (1.1–16.2)
- Respiratory illness 2.5 (0.5–16.3)

Studies conducted in South America

Guatemala (indigenous group)
2004
Schei et al. [21]
Transversal1058 children between 4–6 years of age- Asthma diagnosed
- Occasional wheezing in the last 12 months, induced by exercise in the last year, no. of episodes in the last year ( 4 )
- Night cough in the last year
- Alterations in sleeping habits
- Speech limitations
- All severe criteria.
Q (ISAAC)Use of wood for cooking fuel( ) cooker with exhaust chimney
( ) mix of gas and open fire cooking
( ) open fire cooking
( ) 51.5%
( ) 10.4%
( ) 38.1%
OR for open fire cooking
wheezing:
- Occasional: 2.0 (1.1–3.7)
- Last 12 m: 3.4 (1.3–8.5)
- Induced by exercise in the past year: 3.5 (1.4–8.6)
- Speech limitations: 3.4 (1.1–11.3)

Studies conducted in the United States

Connecticut and Virginia
2002
Triche et al. [9]
Birth cohort obtained in a hospital890 Children 1 year of ageDays of wheezing
Episodes of wheezing
Days of cough
Episodes of cough
Q/2 weeks-  Wood-burning heater
- Kerosene heater
- Gas heater
Q24.6%
18.1%
17.4%
- Socio-demographics
- Mother: allergies, asthma, education
- No. of children
- Child: breastfed, sex, birth season
- Total days of cough
Wood-burning heater: 1.10 (1.02–1.19)
- Episodes of cough
Kerosene heater: 1.07 (1.00–1.15)
- Other correlations: NS

Arizona
1996
Robin et al. [22]
Case-control
pairing
1–24 months (mean = 7)
45 cases and
45 matched controls.
Children hospitalized with acute lower respiratory tract infections.
Controls: children with health record at the same hospital matched on date of birth and gender.
Energy sources for heating and cookingGas/electric:
Mean = 22.2
MG = 18,8
+ wood heating:
M = 100.9
MG = 57.4
Only wood:
M = 85.6
GM = 62.8
Running water, type of house, no. of rooms, no. of children, distance from clinic/hospital, passive exposure to tobacco smoke.A risk 5 times greater was found for children who lived in houses in which wood was used for cooking, albeit with an ample interval of confidence due to the low number of subjects in this group (8.9% of the cases). The magnitude of correlation decreased less than 20% after adjusting for the potentially confounding variables.

Studies conducted in Europe

Finland
2001
Kilpelainen et al. [23]
Cohorts (retrospective)- Survey administered to 10,667 university students (18–25years) about their first 6 years of life
- (children born in the mid-70s)
QGas heatersQ51.7% Farm
19.4% Rural, not farm
28.9% Urban
- Parents: history of asthma or atopy
- No. of children, pets with hair or feathers, family member who smoked indoors daily, daycare outside the home for children under 2, sex of child
- A correlation was found between living on a farm between the ages of 0-6 and allergic rhinoconjunctivitis 0.61 (0.5–0.75; ). Living on a farm was frequent for subjects whose homes were heated with wood.

Teplice (Czech Rep.)
2006
Baker et al. [24]
Cohort452 children followed up to the age of threeLower respiratory tract illness (except pneumonia).
ICD-10 J20, J21, J40 and J44.
1049 episodes
(98% acute bronchitis J20)
- Registers from pediatric practices, emergency rooms, and hospitals.
- Q (mothers)
Heating fuels (natural gas, electricity, coal, or wood) and cooking fuels (gas, propane, electricity, coal, or wood)Q?- Parents: age, education, ethnic background of mother. Father’s education and smoking
- Home: temperature and humidity
- Family density, other children 14 years of age
- Child: Sex, breastfed
- Coal stoves
- RR 1.45 (1.07–1.97)
- With breastfeeding: RR 1.33 (0.95–1.86)
- Without breastfeeding: RR 2.77 (1.45–5.27)
- Remaining sources NS

ALRTI: acute lower respiratory tract infections; Q: questionnaire; W: wood; K: kerosene; VOCs: Volatile organic compounds; CO: Carbon Monoxide; CO2: Carbon Dioxide; NO2: Nitrogen Dioxide; NS: not statistically significant.