Plasma Levels of Polychlorinated Biphenyls, Non-Hodgkin Lymphoma, and Causation

Table 5

Summary of the dose-response correlations between synchronized polychlorinated biphenyl (PCB) bioaccumulation and the incidence of cancer. Accumulation is represented as based on sales alone (sales growth), environmental exposure (static growth), and physiologic exposure (dynamic growth).

Cancer type	Statistical correlation with PCB accumulation (𝑅^2)
	Sales only (sales)	Environment (static)	Physiologic (dynamic)
Non-Hodgkin lymphoma	0.9813	0.9427	0.9850
All cancers	0.9754	0.8874	0.3523
Hodgkin lymphoma	0.2077	0.0062	0.0273
Pancreatic	0.0411	0.0979	0.0001
Liver and bile duct	0.8834	0.5960	0.9715
Kidney and renal	0.9399	0.7022	0.9534
Bone and joint	0.1190	0.1156	0.1486
Brain and nervous system	0.7966	0.5746	0.0800
Digestive system	0.0089	0.4168	0.8548
Leukemia	0.0913	0.0248	0.0081
Lung	0.8826	0.5600	0.0236
Skin	0.9166	0.7254	0.9378
Oral	0.4224	0.5994	0.8910
Soft tissue and heart	0.3322	0.5377	0.9118
Urinary bladder	0.7153	0.7050	0.3750
Breast (female)	0.9076	0.8639	0.3546
Genital system (female)	0.6892	0.7718	0.6825
Prostate (male)	0.8369	0.7290	0.3808