Research Article

Relationship between RBC Mercury Levels and Serum n3 Polyunsaturated Fatty Acid Concentrations among Japanese Men and Women

Table 2

RBC mercury concentration and serum EPA and HDL-EPA levels in association with weekly fish consumption.

Weekly fish consumption*1
<23-45-6>7 𝑃 for trend*2

Hg levels in RBC
 Men
   𝑁 14342321
  Mean Hg*3 (ng/g)50.141.735.751.90.643
  95% CI35.0–71.732.2–53.826.5– 48.338.1–70.8
 Women
   𝑁 21794520
  Mean Hg*3 (ng/g)22.125.224.135.10.035
  95% CI15.9–30.721.2–30.119.5– 29.726.1–47.2

Serum EPA levels
 Men
   𝑁 14342321
  Mean EPA*3 (mg/L)55.974.568.378.20.207
  95% CI36.5–85.854.9–101.247.8–97.754.0– 113.2
 Women
   𝑁 21794520
  Mean EPA*3 (mg/L)59.057.560.663.20.582
  95% CI45.8–75.850.7–65.352.1–70.451.2–78.0

EPA levels in serum HDL fraction
 Men
   𝑁 14342321
  Mean*3 (mg/L)21.223.529.633.20.014
  95% CI14.1–31.817.6–31.521.0–41.823.3–47.3
 Women
   𝑁 21794520
  Mean*3 (mg/L)17.921.422.825.00.073
  95% CI13.5–23.718.6–24.719.3–27.019.8–31.5

*1: Raw fish (times/week) + fish-paste products (times/week) + dry-fish (times/week).
*2: When calculating 𝑃 values, age was always included in the models as a covariate. Trend of association was assessed by a regression model assigning consecutive integers to the levels of the weekly fish consumption.
*3: Geometric mean.