| | Lifetime substance use | Substance use in past year | Substance use in past month |
| Age (years) Ref. = 18–34 | | | | 35–49 | 0.83 (0.63, 1.10) | 0.61 (0.44, 0.86)** | 0.55 (0.35, 0.89)* | 50–64 | 0.80 (0.57, 1.12) | 0.26 (0.14, 0.51)*** | 0.47 (0.20, 1.07) | 65 or more | 0.21 (0.10, 0.45)*** | NR | NR | Gender Ref. = Male | | | | Female | 0.61 (0.51, 0.75)*** | 0.74 (0.58, 0.93)* | 0.77 (0.59, 1.02) | Marital status Ref. = not currently married | | | | Currently married | 0.79 (0.64, 0.97)* | 0.53 (0.40, 0.70)*** | 0.47 (0.30, 0.73)** | Poverty Ref. < 100% FPL | | | | 100–199% FPL | 1.06 (0.82, 1.37) | 0.90 (0.66, 1.22) | 0.83 (0.53, 1.28) | ≥200% FPL | 1.48 (1.15, 1.90)** | 0.95 (0.72, 1.25) | 0.97 (0.62, 1.54) | Education Ref. = less than high school | | | | High school graduate | 1.32 (1.06, 1.64)* | 1.05 (0.73, 1.51) | 0.96 (0.65, 1.42) | Some college | 1.54 (1.21, 1.95)** | 0.97 (0.71, 1.33) | 0.80 (0.53, 1.20) | College graduate | 1.32 (0.88, 1.98) | 0.93 (0.60, 1.45) | 0.90 (0.43, 1.86) | Employment status Ref. = currently unemployed | | | | Currently employed | 1.22 (1.00, 1.47)* | 0.96 (0.74, 1.26) | 0.84 (0.60, 1.18) | Lifetime major depressive episode Ref. = No | | | | Yes | 2.97 (2.03, 4.33)*** | 2.22 (1.58, 3.13)*** | 1.75 (1.09, 2.83)* | Religious beliefs influence life Ref. = strongly disagree/disagree | | | | Strongly agree/agree | 0.72 (0.58, 0.91)* | 0.63 (0.49, 0.82)** | 0.59 (0.43, 0.81)** | Language of interview Ref. = English | | | | Spanish | 0.29 (0.23, 0.37)*** | 0.33 (0.22, 0.51)*** | 0.30 (0.17, 0.53)*** | Incarceration Ref. = never booked/arrested | | | | Ever booked/arrested | 5.25 (3.94, 7.00)*** | 2.45 (1.85, 3.24)*** | 3.08 (2.21, 4.29)*** |
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